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Rab proteins geranylgeranyltransferase component

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Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab to a protein acceptor (By similarity).

Below are the list of possible Rab proteins geranylgeranyltransferase component products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Rab proteins geranylgeranyltransferase component A

 Rab proteins geranylgeranyltransferase component A ELISA Kit
 Rab proteins geranylgeranyltransferase component A Recombinant
 Rab proteins geranylgeranyltransferase component A Antibody
Also known as Rab proteins geranylgeranyltransferase component A (Rab escort protein homolog) (REP).
Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab to a protein acceptor ().
 Rep ELISA Kit
 Rep Recombinant
 Rep Antibody
 CG8432 ELISA Kit
 CG8432 Recombinant
 CG8432 Antibody
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Rab proteins geranylgeranyltransferase component A 1

 Rab proteins geranylgeranyltransferase component A 1 ELISA Kit
 Rab proteins geranylgeranyltransferase component A 1 Recombinant
 Rab proteins geranylgeranyltransferase component A 1 Antibody
Also known as Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein homolog) (Rab escort protein 1) (REP-1).
CHM: Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Also
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a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation. Defects in CHM are the cause of choroideremia (CHM). An X-linked recessive disease characterized by a slowly progressive degeneration of the choroid, photoreceptors, and retinal pigment epithelium. Affected males develop night blindness in their teenage years followed by loss of peripheral vision and complete blindness at middle age. Carrier females are generally asymptomatic but funduscopic examination often shows patchy areas of chorioretinal atrophy. Belongs to the Rab GDI family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase

Cellular Component: cytosol; Rab-protein geranylgeranyltransferase complex

Molecular Function: protein binding; Rab GTPase binding

Biological Process: blood vessel development; protein geranylgeranylation; protein targeting to membrane
 Chm ELISA Kit
 Chm Recombinant
 Chm Antibody
 Rep1 ELISA Kit
 Rep1 Recombinant
 Rep1 Antibody
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Rab proteins geranylgeranyltransferase component A 2

 Rab proteins geranylgeranyltransferase component A 2 ELISA Kit
 Rab proteins geranylgeranyltransferase component A 2 Recombinant
 Rab proteins geranylgeranyltransferase component A 2 Antibody
Also known as Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2).
CHML: Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less ef
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fective than REP-1 in supporting prenylation of Rab3 family. Belongs to the Rab GDI family.

Chromosomal Location of Human Ortholog: 1q43

Cellular Component: cytoplasm; nucleoplasm; Rab-protein geranylgeranyltransferase complex

Molecular Function: Rab GTPase binding

Biological Process: protein geranylgeranylation
 CHML ELISA Kit
 CHML Recombinant
 CHML Antibody
 REP2 ELISA Kit
 REP2 Recombinant
 REP2 Antibody
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