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Rabankyrin

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Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport.

Below are the list of possible Rabankyrin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Rabankyrin-5

 Rabankyrin-5 ELISA Kit
 Rabankyrin-5 Recombinant
 Rabankyrin-5 Antibody
Also known as Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif).
ANKFY1: a cytoplasmic protein that contains a coiled-coil structure and a BTB/POZ domain at its N-terminus, ankyrin repeats in the middle portion, and a FYVE-finger motif at its C-terminus. This protein belongs to a subgroup of double zinc finger proteins which may be involved in vesicle or protein transport. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Apr 2012]

Chromosomal Location of Human Orthol
>>>
og: 17p13.3

Cellular Component: early endosome; endosome membrane; lysosomal membrane; membrane; retromer complex

Molecular Function: protein binding; Rab GTPase binding

Biological Process: endosomal vesicle fusion; endosome localization; positive regulation of pinocytosis; retrograde transport, endosome to Golgi
 ANKFY1 ELISA Kit
 ANKFY1 Recombinant
 ANKFY1 Antibody
 ANKHZN ELISA Kit
 ANKHZN Recombinant
 ANKHZN Antibody
 KIAA1255 ELISA Kit
 KIAA1255 Recombinant
 KIAA1255 Antibody
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