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Rac GTPase-activating protein

Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

Below are the list of possible Rac GTPase-activating protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Rac GTPase-activating protein 1

 Rac GTPase-activating protein 1 ELISA Kit
 Rac GTPase-activating protein 1 Recombinant
 Rac GTPase-activating protein 1 Antibody
Also known as Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP).
MgcRacGAP: a rac GTPase activating protein. Plays an important role in cytokinesis by regulating cortical movement through RhoA. Phosphorylation by Aurora B apparently induces GAP activity toward RhoA.

Protein type: GAPs; GAPs, Rac/Rho

Cellular Component: cleavage furrow; cytoplasm; extrinsic to int
ernal side of plasma membrane; midbody; nucleoplasm; nucleus; spindle midzone

Molecular Function: alpha-tubulin binding; beta-tubulin binding; gamma-tubulin binding; GTPase activator activity; microtubule binding; phosphatidylinositol-3,4,5-triphosphate binding; protein kinase binding

Biological Process: cytokinesis after mitosis; cytokinesis, contractile ring formation; embryonic development; neuroblast proliferation; positive regulation of cytokinesis; regulation of attachment of spindle microtubules to kinetochore; regulation of GTPase activity; spindle midzone assembly involved in mitosis; sulfate transport
 Racgap1 ELISA Kit
 Racgap1 Recombinant
 Racgap1 Antibody
 Mgcracgap ELISA Kit
 Mgcracgap Recombinant
 Mgcracgap Antibody
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