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Radiation-inducible immediate-early gene

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May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.

Below are the list of possible Radiation-inducible immediate-early gene products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Radiation-inducible immediate-early gene IEX-1

 Radiation-inducible immediate-early gene IEX-1 ELISA Kit
 Radiation-inducible immediate-early gene IEX-1 Recombinant
 Radiation-inducible immediate-early gene IEX-1 Antibody
Also known as Radiation-inducible immediate-early gene IEX-1 (Differentiation-dependent gene 2 protein) (Protein DIF-2) (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1).
IEX-1: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A- PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. Belongs to the IER3 family.

Protein type: Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Compo
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nent: cytosol; nucleus

Molecular Function: protein binding

Biological Process: anatomical structure morphogenesis; apoptosis; regulation of phosphoinositide 3-kinase cascade
 IER3 ELISA Kit
 IER3 Recombinant
 IER3 Antibody
 DIF2 ELISA Kit
 DIF2 Recombinant
 DIF2 Antibody
 IEX1 ELISA Kit
 IEX1 Recombinant
 IEX1 Antibody
 PRG1 ELISA Kit
 PRG1 Recombinant
 PRG1 Antibody
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