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RalA-binding protein

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Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Below are the list of possible RalA-binding protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

RalA-binding protein 1

 RalA-binding protein 1 ELISA Kit
 RalA-binding protein 1 Recombinant
 RalA-binding protein 1 Antibody
Also known as RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (Ral-interacting protein 1).
RALBP1: Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. S
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erves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin. Interacts with the GTP-bound form of RALA, RALB, CDC42 and RAC1. Interacts with REPS1 and REPS2 and this does not affect the Ral-binding activity. Interacts with DAB2IP. Interacts with catalytically active CCNB1 and CDK1 during mitosis. Interacts with EPN1, NUMB and TFAP2A during interphase and mitosis. Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 18p11.3

Cellular Component: cytosol; membrane

Molecular Function: ATPase activity; ATPase activity, coupled to movement of substances; GTPase activator activity; protein binding; Rac GTPase binding; Ral GTPase binding; transmembrane transporter activity

Biological Process: chemotaxis; endocytosis; positive regulation of GTPase activity; regulation of GTPase activity; regulation of small GTPase mediated signal transduction; signal transduction; small GTPase mediated signal transduction; transmembrane transport; transport
 RALBP1 ELISA Kit
 RALBP1 Recombinant
 RALBP1 Antibody
 RLIP1 ELISA Kit
 RLIP1 Recombinant
 RLIP1 Antibody
 RLIP76 ELISA Kit
 RLIP76 Recombinant
 RLIP76 Antibody
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RalA-binding protein 1-A

 RalA-binding protein 1-A ELISA Kit
 RalA-binding protein 1-A Recombinant
 RalA-binding protein 1-A Antibody
Also known as RalA-binding protein 1-A (RalBP1-A) (Ral-interacting protein 1-A) (RIP1-A) (XRLIP2) (XRLIP76-A).
A ralB effector; necessary for the ralB pathway to act on the cytoskeleton, to regulate pigment distribution and to regulate gastrulation.
 ralbp1-a ELISA Kit
 ralbp1-a Recombinant
 ralbp1-a Antibody
 rlip ELISA Kit
 rlip Recombinant
 rlip Antibody
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