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RalBP1-associated Eps domain-containing protein

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May coordinate the cellular actions of activated EGF receptors and Ral-GTPases.

Below are the list of possible RalBP1-associated Eps domain-containing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

RalBP1-associated Eps domain-containing protein 1

 RalBP1-associated Eps domain-containing protein 1 ELISA Kit
 RalBP1-associated Eps domain-containing protein 1 Recombinant
 RalBP1-associated Eps domain-containing protein 1 Antibody
Also known as RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).
REPS1: a vesicle-associated protein that influences endocytosis through its ability to interact with Rab11FIP2 and RALBP1. An EGFR substrate that interacts with CRK and GRB2. May coordinate the cellular actions of activated EGF receptors and Ral-GTPases. Binding to RALBP1 does not affect its Ral-bind
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ing activity. Forms a complex with the SH3 domains of CRK and GRB2. Three alternatively spliced isoforms have been described.

Protein type: Vesicle

Cellular Component: coated pit; plasma membrane

Molecular Function: protein binding; SH3 domain binding
 Reps1 ELISA Kit
 Reps1 Recombinant
 Reps1 Antibody
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RalBP1-associated Eps domain-containing protein 2

 RalBP1-associated Eps domain-containing protein 2 ELISA Kit
 RalBP1-associated Eps domain-containing protein 2 Recombinant
 RalBP1-associated Eps domain-containing protein 2 Antibody
Also known as RalBP1-associated Eps domain-containing protein 2 (Partner of RalBP1) (RalBP1-interacting protein 2).
REPS2: an adaptor protein involved in growth factor signaling through its influence on the Ral, a small G protein that regulates endocytosis of EGF and insulin receptors. Interacts with DDEF1, paxillin, RALBP1 and GRB2. Binding to RALBP1 does not affect the Ral-binding activity of
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the latter. Forms a ternary complex with activated Ral and RALBP1. Binds epsin 1. Relatively highly expressed in androgen-dependent as compared to androgen-independent prostate cancer cell lines and xenografts. EGF receptor internalization and signalling is inhibited by increased expression of REPS2. EGF stimulates phosphorylation on Tyr-residues and induces complex formation with EGF receptor through an adapter protein such as GRB2. Two alternatively spliced isoforms have been described. Isoform 2 is down-regulated during progression of prostate cancer.

Protein type: Adaptor/scaffold; G protein regulator, misc.

Chromosomal Location of Human Ortholog: Xp22.2

Molecular Function: protein binding

Biological Process: epidermal growth factor receptor signaling pathway; protein complex assembly
 REPS2 ELISA Kit
 REPS2 Recombinant
 REPS2 Antibody
 POB1 ELISA Kit
 POB1 Recombinant
 POB1 Antibody
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