| Rap guanine nucleotide exchange factor 3 ELISA Kit|
Rap guanine nucleotide exchange factor 3 Recombinant
Rap guanine nucleotide exchange factor 3 Antibody
|Also known as Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI). |
Epac1: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, misc.
Cellular Component: apical part of cell;
basal plasma membrane; brush border membrane; cell soma; cortical actin cytoskeleton; filopodium; growth cone; lamellipodium; microvillus; nerve terminal; perinuclear region of cytoplasm; plasma membrane
Molecular Function: cAMP binding; guanyl-nucleotide exchange factor activity; protein domain specific binding; Rap guanyl-nucleotide exchange factor activity
Biological Process: negative regulation of collagen biosynthetic process; positive regulation of angiogenesis; positive regulation of cell size; positive regulation of GTPase activity; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein amino acid phosphorylation; positive regulation of protein export from nucleus; positive regulation of smooth muscle cell migration; positive regulation of stress fiber formation; positive regulation of syncytium formation by plasma membrane fusion; positive regulation of transcription from RNA polymerase II promoter; Rap protein signal transduction
| Rapgef3 ELISA Kit|
| Epac ELISA Kit|
| Epac1 ELISA Kit|