Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Ras-related C3 botulinum toxin substrate  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • CNNM2 Antibody
 • PLK3 Antibody
 • Mullerian Inhibiting Substance-Mullerian Hormone (MIS-AMH) ELISA Kit
 • Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit
 • Stomatin Like Protein 2 (SLP-2) ELISA Kit
 • Phosphatidyl Ethanol (PEth) ELISA Kit
 • Extracellular Matrix Protein 1 (ECM1) ELISA Kit
 • Apolipoprotein A1 (APOA1) ELISA Kit
 • Aminopeptidase (AMP) ELISA Kit
 • Protein Tyrosine Phosphatase Receptor Type B (PTPRB) ELISA Kit
 • Prostaglandin E Receptor 2 (EP2) ELISA Kit
 • Skeletal Muscle Actinin-alpha (SM ACTININ-alpha) ELISA Kit
 • Interleukin 3 (IL-3) ELISA Kit
 • Thyroid Peroxidase Antibody (TPO) ELISA Kit
 downarrow more ...
separator

Ras-related C3 botulinum toxin substrate

separator
Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates PKN2 kinase activity. In concert with RAB7A, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. In glioma cells, promotes cell migration and invasion. In podocytes, promotes nuclear shuttling of NR3C2; this modulation is required for a proper kidney functioning. Required for atypical chemokine receptor ACKR2-induced LIMK1-PAK1-dependent phosphorylation of cofilin (CFL1) and for up-regulation of ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. In synapses, seems to mediate the regulation of F-actin cluster formation performed by SHANK3.; Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction.

Below are the list of possible Ras-related C3 botulinum toxin substrate products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Ras-related C3 botulinum toxin substrate 1

 Ras-related C3 botulinum toxin substrate 1 ELISA Kit
 Ras-related C3 botulinum toxin substrate 1 Recombinant
 Ras-related C3 botulinum toxin substrate 1 Antibody
Also known as Ras-related C3 botulinum toxin substrate 1 (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1).
RAC1: a plasma membrane-associated member of the Rho-GTPase family. Plays a key role in cytoskeletal reorganization, membrane trafficking, transcriptional regulation and cell growth and development. GTP binding stimulates its activity. Phosphorylation by Akt may inhibit GTP binding of Rac1, therefore attenuating the downstream signal transduction pathway. Found in a trimeric complex composed of DOCK1 and ELMO1, which plays a central role in phagocytosis of ap
>>>
optotic cells. Two alternatively spliced isoforms have been described.

Protein type: G protein; G protein, monomeric; G protein, monomeric, Rho; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: actin filament; cytoplasm; cytosol; endoplasmic reticulum membrane; extracellular matrix; focal adhesion; lamellipodium; membrane; plasma membrane; trans-Golgi network

Molecular Function: enzyme binding; GTP binding; GTPase activity; protein binding; Rho GDP-dissociation inhibitor binding; thioesterase binding

Biological Process: actin cytoskeleton organization and biogenesis; actin filament polymerization; anatomical structure morphogenesis; blood coagulation; cell adhesion; cell motility; cell motility involved in cell locomotion; ephrin receptor signaling pathway; inflammatory response; lamellipodium biogenesis; localization within membrane; negative regulation of interleukin-23 production; negative regulation of receptor-mediated endocytosis; platelet activation; positive regulation of apoptosis; positive regulation of focal adhesion formation; positive regulation of protein amino acid phosphorylation; positive regulation of Rho protein signal transduction; positive regulation of stress fiber formation; regulation of cell migration; regulation of cell size; regulation of defense response to virus by virus; regulation of hydrogen peroxide metabolic process; regulation of small GTPase mediated signal transduction; response to wounding; ruffle organization and biogenesis; T cell costimulation; vascular endothelial growth factor receptor signaling pathway; Wnt receptor signaling pathway, planar cell polarity pathway
 RAC1 ELISA Kit
 RAC1 Recombinant
 RAC1 Antibody
 TC25 ELISA Kit
 TC25 Recombinant
 TC25 Antibody
 MIG5 ELISA Kit
 MIG5 Recombinant
 MIG5 Antibody
Table BarTOPTable Bar
 

Ras-related C3 botulinum toxin substrate 2

 Ras-related C3 botulinum toxin substrate 2 ELISA Kit
 Ras-related C3 botulinum toxin substrate 2 Recombinant
 Ras-related C3 botulinum toxin substrate 2 Antibody
Also known as Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2).
RAC2: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augmen
>>>
ts the production of reactive oxygen species (ROS) by NADPH oxidase. Interacts with DOCK2, which may activate it. Hematopoietic specific. Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP, GTPase activating proteins (GAPs) which increase the GTP hydrolysis activity, and GDP dissociation inhibitors which inhibit the dissociation of the nucleotide from the GTPase. Belongs to the small GTPase superfamily. Rho family.

Protein type: G protein; G protein, monomeric; G protein, monomeric, Rho; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: actin filament; cytosol; focal adhesion; lamellipodium; phagocytic vesicle membrane; plasma membrane

Molecular Function: GTP binding

Biological Process: actin filament organization; platelet activation; regulation of hydrogen peroxide metabolic process; regulation of small GTPase mediated signal transduction; signal transduction

Disease: Neutrophil Immunodeficiency Syndrome
 RAC2 ELISA Kit
 RAC2 Recombinant
 RAC2 Antibody
Table BarTOPTable Bar
 

Ras-related C3 botulinum toxin substrate 3

 Ras-related C3 botulinum toxin substrate 3 ELISA Kit
 Ras-related C3 botulinum toxin substrate 3 Recombinant
 Ras-related C3 botulinum toxin substrate 3 Antibody
Also known as Ras-related C3 botulinum toxin substrate 3 (p21-Rac3).
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Alternative splicing resul
>>>
ts in multiple transcript variants. [provided by RefSeq, Oct 2015]
 RAC3 ELISA Kit
 RAC3 Recombinant
 RAC3 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions