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Receptor-type tyrosine-protein phosphatase

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Possesses an intrinsic protein tyrosine phosphatase (PTPase) activity .

Below are the list of possible Receptor-type tyrosine-protein phosphatase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Receptor-type tyrosine-protein phosphatase

 Receptor-type tyrosine-protein phosphatase ELISA Kit
 Receptor-type tyrosine-protein phosphatase Recombinant
 Receptor-type tyrosine-protein phosphatase Antibody
Possesses an intrinsic protein tyrosine phosphatase (PTPase) activity (PubMed:9585503). Regulates egl-15 activity which is required for hypodermis-mediated fluid homeostasis and protein degradation in muscle (PubMed:9585503). During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles (PubMed:16495308). Plays a role in nicoti
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nic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine (PubMed:15990870). Regulates synaptic levels of nAchR subunit lev-1 in the nerve cord (PubMed:15990870).
 clr-1 ELISA Kit
 clr-1 Recombinant
 clr-1 Antibody
 F56D1.4 ELISA Kit
 F56D1.4 Recombinant
 F56D1.4 Antibody
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Receptor-type tyrosine-protein phosphatase alpha

 Receptor-type tyrosine-protein phosphatase alpha ELISA Kit
 Receptor-type tyrosine-protein phosphatase alpha Recombinant
 Receptor-type tyrosine-protein phosphatase alpha Antibody
Also known as Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).
PTPRA: a receptor protein tyrosine phosphatase (PTP). Contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. Dephosphorylates and activates Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Four alternatively spliced isoforms have been reported.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor pro
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tein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: integral to plasma membrane; plasma membrane; receptor complex

Molecular Function: protein binding; protein tyrosine phosphatase activity; Ras guanyl-nucleotide exchange factor activity; transmembrane receptor protein tyrosine phosphatase activity

Biological Process: axon guidance; MAPKKK cascade
 PTPRA ELISA Kit
 PTPRA Recombinant
 PTPRA Antibody
 PTPA ELISA Kit
 PTPA Recombinant
 PTPA Antibody
 PTPRL2 ELISA Kit
 PTPRL2 Recombinant
 PTPRL2 Antibody
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Receptor-type tyrosine-protein phosphatase beta

 Receptor-type tyrosine-protein phosphatase beta ELISA Kit
 Receptor-type tyrosine-protein phosphatase beta Recombinant
 Receptor-type tyrosine-protein phosphatase beta Antibody
Also known as Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP).
PTPRB: Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK
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/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin. Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 12q15-q21

Cellular Component: integral to plasma membrane; receptor complex

Molecular Function: protein binding; transmembrane receptor protein tyrosine phosphatase activity

Biological Process: dephosphorylation; phosphate metabolic process; protein amino acid dephosphorylation
 PTPRB ELISA Kit
 PTPRB Recombinant
 PTPRB Antibody
 PTPB ELISA Kit
 PTPB Recombinant
 PTPB Antibody
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Receptor-type tyrosine-protein phosphatase C

 Receptor-type tyrosine-protein phosphatase C ELISA Kit
 Receptor-type tyrosine-protein phosphatase C Recombinant
 Receptor-type tyrosine-protein phosphatase C Antibody
Also known as Receptor-type tyrosine-protein phosphatase C (Leukocyte common antigen) (CD antigen CD45).
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor.
 ptprc ELISA Kit
 ptprc Recombinant
 ptprc Antibody
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Receptor-type tyrosine-protein phosphatase delta

 Receptor-type tyrosine-protein phosphatase delta ELISA Kit
 Receptor-type tyrosine-protein phosphatase delta Recombinant
 Receptor-type tyrosine-protein phosphatase delta Antibody
Also known as Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta).
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contai
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ns an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]
 PTPRD ELISA Kit
 PTPRD Recombinant
 PTPRD Antibody
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Receptor-type tyrosine-protein phosphatase dep-1

 Receptor-type tyrosine-protein phosphatase dep-1 ELISA Kit
 Receptor-type tyrosine-protein phosphatase dep-1 Recombinant
 Receptor-type tyrosine-protein phosphatase dep-1 Antibody
Also known as Receptor-type tyrosine-protein phosphatase dep-1 (Density-enhanced phosphatase homolog 1).
Probable phosphatase which may dephosphorylate receptor let-23 and thereby regulate cell fate during the development of the vulva and the excretory system. By inhibiting let-23 signaling prevents the establishment of a primary cell fate in the descendants of vulva precursor cells P5.p and P7
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.p. Similarly, may prevent duct cell fate in ABpr precursor.
 dep-1 ELISA Kit
 dep-1 Recombinant
 dep-1 Antibody
 F44G4.8 ELISA Kit
 F44G4.8 Recombinant
 F44G4.8 Antibody
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Receptor-type tyrosine-protein phosphatase epsilon

 Receptor-type tyrosine-protein phosphatase epsilon ELISA Kit
 Receptor-type tyrosine-protein phosphatase epsilon Recombinant
 Receptor-type tyrosine-protein phosphatase epsilon Antibody
Also known as Receptor-type tyrosine-protein phosphatase epsilon (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).
PTPRE: a cytoplasmic and transmembrane receptor protein tyrosine phosphatase that regulates IL-10 and TNFA biosynthesis, myelination and cell-matrix adhesion, overexpression reduces tumor development

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polar
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ity/chemotaxis; Receptor protein phosphatase, tyrosine

Cellular Component: cytoplasm; nucleus; plasma membrane

Molecular Function: protein homodimerization activity; protein tyrosine phosphatase activity

Biological Process: negative regulation of insulin receptor signaling pathway; regulation of mast cell activation; transmembrane receptor protein tyrosine phosphatase signaling pathway
 Ptpre ELISA Kit
 Ptpre Recombinant
 Ptpre Antibody
 Ptpe ELISA Kit
 Ptpe Recombinant
 Ptpe Antibody
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Receptor-type tyrosine-protein phosphatase eta

 Receptor-type tyrosine-protein phosphatase eta ELISA Kit
 Receptor-type tyrosine-protein phosphatase eta Recombinant
 Receptor-type tyrosine-protein phosphatase eta Antibody
Also known as Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148).
PTPRJ: Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAP
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K1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation. Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling. Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: cell surface; immunological synapse; integral to plasma membrane; intercellular junction; plasma membrane

Molecular Function: beta-catenin binding; gamma-catenin binding; mitogen-activated protein kinase binding; phosphoric monoester hydrolase activity; platelet-derived growth factor receptor binding; protein binding; protein kinase binding; protein tyrosine phosphatase activity

Biological Process: negative regulation of cell growth; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of MAP kinase activity; negative regulation of protein kinase B signaling cascade; negative regulation of T cell receptor signaling pathway; negative regulation of vascular permeability; platelet-derived growth factor receptor signaling pathway; positive chemotaxis; positive regulation of cell adhesion; positive regulation of focal adhesion formation; positive regulation of protein kinase B signaling cascade; regulation of cell adhesion; T cell receptor signaling pathway

Disease: Colorectal Cancer
 PTPRJ ELISA Kit
 PTPRJ Recombinant
 PTPRJ Antibody
 DEP1 ELISA Kit
 DEP1 Recombinant
 DEP1 Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase F

 Receptor-type tyrosine-protein phosphatase F ELISA Kit
 Receptor-type tyrosine-protein phosphatase F Recombinant
 Receptor-type tyrosine-protein phosphatase F Antibody
Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) ().
 ptprf ELISA Kit
 ptprf Recombinant
 ptprf Antibody
 si:dkey-21k10.1 ELISA Kit
 si:dkey-21k10.1 Recombinant
 si:dkey-21k10.1 Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase gamma

 Receptor-type tyrosine-protein phosphatase gamma ELISA Kit
 Receptor-type tyrosine-protein phosphatase gamma Recombinant
 Receptor-type tyrosine-protein phosphatase gamma Antibody
Also known as Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).
PTPRG: Possesses tyrosine phosphatase activity. Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chem
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otaxis; Phosphatase; Receptor protein phosphatase, tyrosine

Cellular Component: extracellular space

Molecular Function: identical protein binding; protein tyrosine phosphatase activity
 Ptprg ELISA Kit
 Ptprg Recombinant
 Ptprg Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase H

 Receptor-type tyrosine-protein phosphatase H ELISA Kit
 Receptor-type tyrosine-protein phosphatase H Recombinant
 Receptor-type tyrosine-protein phosphatase H Antibody
Also known as Receptor-type tyrosine-protein phosphatase H (R-PTP-H) (Stomach cancer-associated protein tyrosine phosphatase 1) (SAP-1) (Transmembrane-type protein-tyrosine phosphatase type H).
PTPRH: May contribute to contact inhibition of cell growth and motility by mediating the dephosphorylation of focal adhesion- associated substrates and thus negatively regulating integrin- promoted signa
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ling processes. Induces apoptotic cell death by at least two distinct mechanisms: inhibition of cell survival signaling mediated by PI 3-kinase, Akt, and ILK and activation of a caspase-dependent proapoptotic pathway. Inhibits the basal activity of LCK and its activation in response to TCR stimulation and TCR-induced activation of MAP kinase and surface expression of CD69. Inhibits TCR-induced tyrosine phosphorylation of LAT and ZAP70. Inhibits both basal activity of DOK1 and its CD2-induced tyrosine phosphorylation. Induces dephosphorylation of p130cas, focal adhesion kinase and c-Src. Reduces migratory activity of Jurkat cells. Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: integral to plasma membrane

Molecular Function: protein binding

Biological Process: protein amino acid dephosphorylation
 PTPRH ELISA Kit
 PTPRH Recombinant
 PTPRH Antibody
 SAP1 ELISA Kit
 SAP1 Recombinant
 SAP1 Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase kappa

 Receptor-type tyrosine-protein phosphatase kappa ELISA Kit
 Receptor-type tyrosine-protein phosphatase kappa Recombinant
 Receptor-type tyrosine-protein phosphatase kappa Antibody
Also known as Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).
PTPRK: a receptor tyrosine phosphatase involved in processes including cell contact and adhesion, growth, tumor invasion, and metastasis. Is a negative regulator of EGFR signaling. Forms complexes with beta-catenin and gamma-catenin, and may modulate the phosphorylation status of b
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eta-catenin. Absent or down-regulated in multiple melanoma cell lines and some melanoma tumors. The gene lies in a region frequently deleted in hematological neoplasms, melanomas, ovary carcinomas, and many other solid tumors. Can play a dual role of tumor suppressor and tumor promoter in mammary epithelial cells. Overexpression results in inhibition of basal proliferation and EGFR signaling in cancer cells. A key regulator of EGFR tyrosine phosphorylation and function in human keratinocytes. TGF-beta 1 stimulates its expression, which may be important for the inhibition of keratinocyte proliferation. Belongs to the protein-tyrosine phosphatase family, receptor class 2B subfamily. Four isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 6q22.2-q22.3

Cellular Component: cell surface; intercellular junction

Molecular Function: beta-catenin binding; gamma-catenin binding; protein binding; protein kinase binding; protein tyrosine phosphatase activity

Biological Process: cell adhesion; cell migration; focal adhesion formation; negative regulation of cell cycle; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of transcription, DNA-dependent; protein amino acid dephosphorylation; signal transduction; transforming growth factor beta receptor signaling pathway
 PTPRK ELISA Kit
 PTPRK Recombinant
 PTPRK Antibody
 PTPK ELISA Kit
 PTPK Recombinant
 PTPK Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase mu

 Receptor-type tyrosine-protein phosphatase mu ELISA Kit
 Receptor-type tyrosine-protein phosphatase mu Recombinant
 Receptor-type tyrosine-protein phosphatase mu Antibody
Also known as Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu).
PTPRM: a single-pass type I membrane protein involved in cell-cell adhesion through homophilic interactions. A protein-tyrosine phosphatase receptor of the class 2B subfamily. A negative regulator of proliferation and invasion of breast cancer cells. The PTPRM gene is frequently hypermethyl
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ated in sporadic cancers. Modulates p120 catenin phosphorylation, promoting adipogenic differentiation. Two isoforms of the human protein have been reported.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Phosphatase; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 18p11.2

Cellular Component: cell-cell adherens junction; cytoplasm; intercellular junction; lamellipodium; perinuclear region of cytoplasm

Molecular Function: cadherin binding; identical protein binding; protein binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity

Biological Process: homophilic cell adhesion; negative regulation of angiogenesis; negative regulation of endothelial cell proliferation; neurite development; protein amino acid dephosphorylation; response to drug; retinal ganglion cell axon guidance; signal transduction
 PTPRM ELISA Kit
 PTPRM Recombinant
 PTPRM Antibody
 PTPRL1 ELISA Kit
 PTPRL1 Recombinant
 PTPRL1 Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase N2

 Receptor-type tyrosine-protein phosphatase N2 ELISA Kit
 Receptor-type tyrosine-protein phosphatase N2 Recombinant
 Receptor-type tyrosine-protein phosphatase N2 Antibody
Also known as Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (Islet cell autoantigen-related protein) (IAR) (ICAAR) (Phogrin).
PTPRN2: Implicated in development of nervous system and pancreatic endocrine cells. Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.
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1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 7q36

Cellular Component: integral to plasma membrane; receptor complex; secretory granule membrane; synaptic vesicle membrane

Molecular Function: transmembrane receptor protein tyrosine phosphatase activity

Biological Process: neurotransmitter secretion; protein amino acid dephosphorylation
 PTPRN2 ELISA Kit
 PTPRN2 Recombinant
 PTPRN2 Antibody
 KIAA0387 ELISA Kit
 KIAA0387 Recombinant
 KIAA0387 Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase O

 Receptor-type tyrosine-protein phosphatase O ELISA Kit
 Receptor-type tyrosine-protein phosphatase O Recombinant
 Receptor-type tyrosine-protein phosphatase O Antibody
Also known as Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2).
PTPRO: Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function. Defects in PTPRO are the cause of nephrotic syndrome type 6 (NPHS6). NPHS6 is a renal disease characterized clinically by proteinuria, hypoalbuminemia, hyperlipidemia and edema. Kidney biopsies show non-specific histologic changes such as focal segmental g
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lomerulosclerosis and diffuse mesangial proliferation. Some affected individuals have an inherited steroid-resistant form and progress to end-stage renal failure. Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 12p13.3-p13.2|12p13-p12

Cellular Component: apical plasma membrane; axon; dendritic spine; growth cone; integral to membrane; lamellipodium; lateral plasma membrane; neuron projection; plasma membrane

Molecular Function: phosphoric monoester hydrolase activity; protein binding; protein homodimerization activity; protein tyrosine phosphatase activity; Wnt-protein binding

Biological Process: axon guidance; cell morphogenesis; glomerulus development; lamellipodium biogenesis; monocyte chemotaxis; negative regulation of glomerular filtration; protein amino acid dephosphorylation; regulation of glomerular filtration

Disease: Nephrotic Syndrome, Type 6
 PTPRO ELISA Kit
 PTPRO Recombinant
 PTPRO Antibody
 GLEPP1 ELISA Kit
 GLEPP1 Recombinant
 GLEPP1 Antibody
 PTPU2 ELISA Kit
 PTPU2 Recombinant
 PTPU2 Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase R

 Receptor-type tyrosine-protein phosphatase R ELISA Kit
 Receptor-type tyrosine-protein phosphatase R Recombinant
 Receptor-type tyrosine-protein phosphatase R Antibody
Also known as Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1).
PTP-SL: Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily. 3 isoforms of the human protein are produced by alternative sp
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licing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: cell junction; cytoplasm; extracellular space; plasma membrane

Molecular Function: protein binding; protein kinase binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity

Biological Process: in utero embryonic development; protein amino acid dephosphorylation
 PTPRR ELISA Kit
 PTPRR Recombinant
 PTPRR Antibody
 ECPTP ELISA Kit
 ECPTP Recombinant
 ECPTP Antibody
 PTPRQ ELISA Kit
 PTPRQ Recombinant
 PTPRQ Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase S

 Receptor-type tyrosine-protein phosphatase S ELISA Kit
 Receptor-type tyrosine-protein phosphatase S Recombinant
 Receptor-type tyrosine-protein phosphatase S Antibody
Also known as Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (Leukocyte common antigen-related protein-tyrosine phosphatase 2) (LAR-PTP2) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma).
PTPRD: is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differ
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entiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Molecular Function: protein tyrosine phosphatase activity

Biological Process: cerebellum development; cerebral cortex development; corpus callosum development; hippocampus development; spinal cord development
 Ptprs ELISA Kit
 Ptprs Recombinant
 Ptprs Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase T

 Receptor-type tyrosine-protein phosphatase T ELISA Kit
 Receptor-type tyrosine-protein phosphatase T Recombinant
 Receptor-type tyrosine-protein phosphatase T Antibody
Also known as Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho).
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
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This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
 PTPRT ELISA Kit
 PTPRT Recombinant
 PTPRT Antibody
 KIAA0283 ELISA Kit
 KIAA0283 Recombinant
 KIAA0283 Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase U

 Receptor-type tyrosine-protein phosphatase U ELISA Kit
 Receptor-type tyrosine-protein phosphatase U Recombinant
 Receptor-type tyrosine-protein phosphatase U Antibody
Also known as Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (Ftp-1) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase-lamda) (PTP-lambda) (PTPlambda) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi).
PTPRU: Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis. Belongs to the protein-tyrosine phosphatase family. Receptor class 2B s
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ubfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Cellular Component: intercellular junction

Molecular Function: beta-catenin binding; protein tyrosine phosphatase activity

Biological Process: cell-cell adhesion; homotypic cell-cell adhesion; negative regulation of cell migration; negative regulation of cell proliferation; protein amino acid dephosphorylation; Wnt receptor signaling pathway through beta-catenin
 Ptpru ELISA Kit
 Ptpru Recombinant
 Ptpru Antibody
 Pcp2 ELISA Kit
 Pcp2 Recombinant
 Pcp2 Antibody
 Ptpf ELISA Kit
 Ptpf Recombinant
 Ptpf Antibody
Table BarTOPTable Bar
 

Receptor-type tyrosine-protein phosphatase V

 Receptor-type tyrosine-protein phosphatase V ELISA Kit
 Receptor-type tyrosine-protein phosphatase V Recombinant
 Receptor-type tyrosine-protein phosphatase V Antibody
Also known as Receptor-type tyrosine-protein phosphatase V (R-PTP-V) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).
Ptprv: May play a role in the maintenance of pluripotency. Down-regulated during differentiation

Protein type: EC 3.1.3.48

Biological Process: cellular lipid catabolic process; cellular response to insulin stimulus; DNA damage response, sig
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nal transduction by p53 class mediator resulting in cell cycle arrest; G1 DNA damage checkpoint; glucose homeostasis; negative regulation of cell proliferation; negative regulation of insulin secretion; pancreas development; protein amino acid carboxylation
 Ptprv ELISA Kit
 Ptprv Recombinant
 Ptprv Antibody
 Esp ELISA Kit
 Esp Recombinant
 Esp Antibody
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Receptor-type tyrosine-protein phosphatase zeta

 Receptor-type tyrosine-protein phosphatase zeta ELISA Kit
 Receptor-type tyrosine-protein phosphatase zeta Recombinant
 Receptor-type tyrosine-protein phosphatase zeta Antibody
Also known as Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta).
PTPRZ1: May be involved in the regulation of specific developmental processes in the CNS. Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/c
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hemotaxis; Receptor protein phosphatase, tyrosine

Cellular Component: axon; cell soma; cytoplasm; dendrite; dendritic spine; extracellular space; filopodium; growth cone; intrinsic to plasma membrane; lamellipodium; membrane; postsynaptic membrane; proteinaceous extracellular matrix

Molecular Function: fibroblast growth factor binding; phosphoric monoester hydrolase activity; protein binding; protein tyrosine phosphatase activity

Biological Process: axonal fasciculation; axonogenesis; hemopoietic progenitor cell differentiation; learning and/or memory; negative regulation of cell proliferation; oligodendrocyte differentiation; positive regulation of cell migration; positive regulation of fibroblast proliferation; positive regulation of peptidyl-tyrosine phosphorylation; protein amino acid dephosphorylation; regulation of dendrite morphogenesis
 Ptprz1 ELISA Kit
 Ptprz1 Recombinant
 Ptprz1 Antibody
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Receptor-type tyrosine-protein phosphatase-like N

 Receptor-type tyrosine-protein phosphatase-like N ELISA Kit
 Receptor-type tyrosine-protein phosphatase-like N Recombinant
 Receptor-type tyrosine-protein phosphatase-like N Antibody
Also known as Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (105 kDa islet cell antigen) (BEM-3) (Brain-enriched membrane-associated protein tyrosine phosphatase) (ICA105) (ICA512) (PTP IA-2) (PTPLP).
PTPRN: Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocyto
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sis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Cellular Component: cell soma; endosome; Golgi apparatus; membrane; nerve terminal; plasma membrane; secretory granule; synapse; synaptic vesicle

Molecular Function: GTPase binding; protein tyrosine phosphatase activity; spectrin binding

Biological Process: cytokine and chemokine mediated signaling pathway; insulin secretion; luteinization; response to cAMP; response to estrogen stimulus; response to glucose stimulus; response to insulin stimulus; response to reactive oxygen species; second-messenger-mediated signaling
 Ptprn ELISA Kit
 Ptprn Recombinant
 Ptprn Antibody
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