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Regulator of telomere elongation helicase

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ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.

Below are the list of possible Regulator of telomere elongation helicase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Regulator of telomere elongation helicase 1

 Regulator of telomere elongation helicase 1 ELISA Kit
 Regulator of telomere elongation helicase 1 Recombinant
 Regulator of telomere elongation helicase 1 Antibody
RTEL1: ATP-dependent DNA helicase required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by promoting the disassembly of D loop recombination intermediates. Also required to regulate telomere length; probably due to its anti-recombinase function. Belongs to the helicase family. RAD3/XPD subfamily. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA repair, damage; EC 3.6.4.12; Helicase

Cellular Component: nucleus
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Molecular Function: ATP binding; ATP-dependent DNA helicase activity; helicase activity; protein binding

Biological Process: DNA duplex unwinding; positive regulation of telomere maintenance; replication fork processing; telomere maintenance; telomere maintenance in response to DNA damage
 Rtel1 ELISA Kit
 Rtel1 Recombinant
 Rtel1 Antibody
 Kiaa1088 ELISA Kit
 Kiaa1088 Recombinant
 Kiaa1088 Antibody
 Rtel ELISA Kit
 Rtel Recombinant
 Rtel Antibody
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Regulator of telomere elongation helicase 1 homolog

 Regulator of telomere elongation helicase 1 homolog ELISA Kit
 Regulator of telomere elongation helicase 1 homolog Recombinant
 Regulator of telomere elongation helicase 1 homolog Antibody
ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as w
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ell as disassembly of D loop recombination intermediates.
 GF20802 ELISA Kit
 GF20802 Recombinant
 GF20802 Antibody
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