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Regulatory factor X-associated protein

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Part of the RFX complex that binds to the X-box of MHC II promoters.

Below are the list of possible Regulatory factor X-associated protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Regulatory factor X-associated protein

 Regulatory factor X-associated protein ELISA Kit
 Regulatory factor X-associated protein Recombinant
 Regulatory factor X-associated protein Antibody
Also known as Regulatory factor X-associated protein (RFX-associated protein).
RFXAP: Part of the RFX complex that binds to the X-box of MHC II promoters. Defects in RFXAP are a cause of bare lymphocyte syndrome type 2 (BLS2); also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency. BLS2 is a severe combined immunodeficiency disease with early onset.
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It is characterized by a profound defect in constitutive and interferon-gamma induced MHC II expression, absence of cellular and humoral T-cell response to antigen challenge, hypogammaglobulinemia and impaired antibody production. The consequence include extreme susceptibility to viral, bacterial and fungal infections.

Protein type: DNA-binding

Cellular Component: nucleus

Molecular Function: DNA binding; transcription coactivator activity

Biological Process: positive regulation of transcription, DNA-dependent
 Rfxap ELISA Kit
 Rfxap Recombinant
 Rfxap Antibody
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