Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Retinoblastoma-like protein  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • G antigen 12G (GAGE12G) Recombinant Protein
 • SCN1B siRNA
 • Mouse Anti-Rat Kappa (kappa chain specific) Secondary Antibody
 • PLK4 cDNA Clone
 • PKC theta Antibody
 • Interferon-gamma (IFNG) Recombinant Protein
 • Sodium Channel Protein Type 10 Subunit Alpha (SCN10A) ELISA Kit
 • Vascuoar endothelial cell growth factor receptor 2, VEGFR-2-... ELISA Kit
 • Interleukin Receptor Associated Kinase (IRAK) ELISA Kit
 • ribosomal protein L28 (rpl28-b) Antibody
 • Glucose Transporter 2 (GLUT2) ELISA Kit
 • Factor VIII:C (FVIII) Antibody
 • Glucose Transporter 5 (GLUT5) ELISA Kit
 • Fatty Acid Binding Protein 3, Muscle and Heart (FABP3) ELISA Kit
 downarrow more ...
separator

Retinoblastoma-like protein

separator
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.

Below are the list of possible Retinoblastoma-like protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Retinoblastoma-like protein 1

 Retinoblastoma-like protein 1 ELISA Kit
 Retinoblastoma-like protein 1 Recombinant
 Retinoblastoma-like protein 1 Antibody
Also known as Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1).
Rb-like 1: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1
>>>
and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor. Belongs to the retinoblastoma protein (RB) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; Tumor suppressor

Chromosomal Location of Human Ortholog: 20q11.2

Cellular Component: nucleoplasm

Molecular Function: protein binding; transcription factor binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter; regulation of lipid kinase activity
 RBL1 ELISA Kit
 RBL1 Recombinant
 RBL1 Antibody
Table BarTOPTable Bar
 

Retinoblastoma-like protein 2

 Retinoblastoma-like protein 2 ELISA Kit
 Retinoblastoma-like protein 2 Recombinant
 Retinoblastoma-like protein 2 Antibody
Also known as Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (PPAR-alpha-interacting complex protein 128) (PRIC128) (Retinoblastoma-related protein 2) (RBR-2) (pRb2).
Rb-like 2: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochrom
>>>
atin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor. Belongs to the retinoblastoma protein (RB) family.

Protein type: Transcription, coactivator/corepressor; Tumor suppressor

Cellular Component: chromatin; cytoplasm; nucleolus; nucleus; transcription factor complex

Molecular Function: protein binding

Biological Process: regulation of lipid kinase activity
 Rbl2 ELISA Kit
 Rbl2 Recombinant
 Rbl2 Antibody
Table BarTOPTable Bar
 

Retinoblastoma-like protein A

 Retinoblastoma-like protein A ELISA Kit
 Retinoblastoma-like protein A Recombinant
 Retinoblastoma-like protein A Antibody
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters (). Plays a dual role, regulating cell-cycle progression and transcriptional events leading to terminal differentiation. In the absence of a G1 phase, functions in late G2 controlling the expression of both S-phase and mitotic gene
>>>
s. Controls stalk/spore preference by suppressing the DIF response in cells destined for the spore pathway. DIF is a chlorinated hydroxyphenone made by cells of spore pathway that promotes stalk differentiation.
 rblA ELISA Kit
 rblA Recombinant
 rblA Antibody
 Rb ELISA Kit
 Rb Recombinant
 Rb Antibody
 DDB0188949 ELISA Kit
 DDB0188949 Recombinant
 DDB0188949 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions