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Retinoic acid receptor

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Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity). Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis.

Below are the list of possible Retinoic acid receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Retinoic acid receptor alpha

 Retinoic acid receptor alpha ELISA Kit
 Retinoic acid receptor alpha Recombinant
 Retinoic acid receptor alpha Antibody
Also known as Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1).
RARA: is a receptor for retinoic acid, a potent mammalian morphogen and teratogen that has profound effects on vertebrate development. RARA is a member of the nuclear receptor superfamily. Controls cell function by directly regulating gene expression. Its phosphorylation is crucial for transc
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riptional activity. Aberrations involving RARA may be a cause of acute promyelocytic leukemia. Two splice-variant isoforms have been described.

Protein type: DNA-binding; Nuclear receptor; Oncoprotein; Transcription factor

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: actin cytoskeleton; cell surface; cytoplasm; nuclear chromatin; nucleoplasm; nucleus

Molecular Function: alpha-actinin binding; chromatin DNA binding; enzyme binding; protein binding; protein domain specific binding; protein heterodimerization activity; protein kinase A binding; protein kinase B binding; receptor binding; retinoic acid binding; retinoic acid receptor activity; transcription coactivator activity; transcription corepressor activity; transcription factor activity; transcription factor binding

Biological Process: apoptotic cell clearance; negative regulation of granulocyte differentiation; negative regulation of interferon-gamma production; negative regulation of transcription, DNA-dependent; negative regulation of tumor necrosis factor production; positive regulation of binding; positive regulation of cell cycle; positive regulation of cell proliferation; positive regulation of interleukin-13 production; positive regulation of interleukin-4 production; positive regulation of interleukin-5 production; positive regulation of T-helper 2 cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein amino acid phosphorylation; response to retinoic acid; retinoic acid receptor signaling pathway; signal transduction; transcription initiation from RNA polymerase II promoter

Disease: Acute Promyelocytic Leukemia
 RARA ELISA Kit
 RARA Recombinant
 RARA Antibody
 NR1B1 ELISA Kit
 NR1B1 Recombinant
 NR1B1 Antibody
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Retinoic acid receptor alpha-A

 Retinoic acid receptor alpha-A ELISA Kit
 Retinoic acid receptor alpha-A Recombinant
 Retinoic acid receptor alpha-A Antibody
Also known as Retinoic acid receptor alpha-A (RAR-alpha-A) (Nuclear receptor subfamily 1 group B member 1-A) (Retinoic acid receptor alpha) (zRAR alpha) (Retinoic acid receptor alpha-2.A) (RAR-alpha-2.A).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (). Required for hindbrain p
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atterning.
 raraa ELISA Kit
 raraa Recombinant
 raraa Antibody
 nr1b1a ELISA Kit
 nr1b1a Recombinant
 nr1b1a Antibody
 rara2a ELISA Kit
 rara2a Recombinant
 rara2a Antibody
 zgc:109797 ELISA Kit
 zgc:109797 Recombinant
 zgc:109797 Antibody
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Retinoic acid receptor alpha-B

 Retinoic acid receptor alpha-B ELISA Kit
 Retinoic acid receptor alpha-B Recombinant
 Retinoic acid receptor alpha-B Antibody
Also known as Retinoic acid receptor alpha-B (RAR-alpha-B) (Nuclear receptor subfamily 1 group B member 1-B) (Retinoic acid receptor alpha-2.B) (RAR-alpha-2.B).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (). Required for hindbrain development and, in lateral plate mesoderm, f
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or specification of the pectoral fins.
 rarab ELISA Kit
 rarab Recombinant
 rarab Antibody
 nr1b1b ELISA Kit
 nr1b1b Recombinant
 nr1b1b Antibody
 rara2b ELISA Kit
 rara2b Recombinant
 rara2b Antibody
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Retinoic acid receptor beta

 Retinoic acid receptor beta ELISA Kit
 Retinoic acid receptor beta Recombinant
 Retinoic acid receptor beta Antibody
Also known as Retinoic acid receptor beta (RAR-beta) (HBV-activated protein) (Nuclear receptor subfamily 1 group B member 2) (RAR-epsilon).
RARB: is a receptor for retinoic acid, a potent mammalian morphogen and teratogen that has profound effects on vertebrate development. RARB is a member of the nuclear receptor superfamily. Controls cell function by directly regulating gene expression. Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain. Four splice-variant isoforms have been described. Isoform beta-1 and beta-2 are nucl
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ear and isoform beta-4 cytoplasmic.

Protein type: Motility/polarity/chemotaxis; Nuclear receptor; Oncoprotein

Chromosomal Location of Human Ortholog: 3p24.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: DNA binding

Biological Process: embryonic gut development; signal transduction; transcription initiation from RNA polymerase II promoter

Disease: Microphthalmia, Syndromic 12
 RARB ELISA Kit
 RARB Recombinant
 RARB Antibody
 HAP ELISA Kit
 HAP Recombinant
 HAP Antibody
 NR1B2 ELISA Kit
 NR1B2 Recombinant
 NR1B2 Antibody
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Retinoic acid receptor gamma

 Retinoic acid receptor gamma ELISA Kit
 Retinoic acid receptor gamma Recombinant
 Retinoic acid receptor gamma Antibody
Also known as Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3).
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elemen
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ts (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
 RARG ELISA Kit
 RARG Recombinant
 RARG Antibody
 NR1B3 ELISA Kit
 NR1B3 Recombinant
 NR1B3 Antibody
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Retinoic acid receptor gamma-A

 Retinoic acid receptor gamma-A ELISA Kit
 Retinoic acid receptor gamma-A Recombinant
 Retinoic acid receptor gamma-A Antibody
Also known as Retinoic acid receptor gamma-A (RAR-gamma-A) (zRAR gamma) (Nuclear receptor subfamily 1 group B member 3-A) (RAR-gamma-2).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (). Required for hindbrain development and for the development of pharyngeal arches.
 rarga ELISA Kit
 rarga Recombinant
 rarga Antibody
 nr1b3a ELISA Kit
 nr1b3a Recombinant
 nr1b3a Antibody
 rarg ELISA Kit
 rarg Recombinant
 rarg Antibody
 rarg2 ELISA Kit
 rarg2 Recombinant
 rarg2 Antibody
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Retinoic acid receptor gamma-B

 Retinoic acid receptor gamma-B ELISA Kit
 Retinoic acid receptor gamma-B Recombinant
 Retinoic acid receptor gamma-B Antibody
Also known as Retinoic acid receptor gamma-B (RAR-gamma-B) (Nuclear receptor subfamily 1 group B member 3-B).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid res
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ponse elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (). Required for hindbrain development.
 rargb ELISA Kit
 rargb Recombinant
 rargb Antibody
 nr1b3b ELISA Kit
 nr1b3b Recombinant
 nr1b3b Antibody
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Retinoic acid receptor RXR

 Retinoic acid receptor RXR ELISA Kit
 Retinoic acid receptor RXR Recombinant
 Retinoic acid receptor RXR Antibody
Also known as Retinoic acid receptor RXR (Retinoid X receptor) (LymRXR).
Ligand-dependent transcription factor probably involved in the retinoic acid response pathway. Binds 9-cis-retinoic acid (). Involved in embryo development, in particular eye and shell formation. May play a role in growth cone steering.
 RXR ELISA Kit
 RXR Recombinant
 RXR Antibody
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Retinoic acid receptor RXR-alpha

 Retinoic acid receptor RXR-alpha ELISA Kit
 Retinoic acid receptor RXR-alpha Recombinant
 Retinoic acid receptor RXR-alpha Antibody
Also known as Retinoic acid receptor RXR-alpha (Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha).
RXRA: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to t
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he retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXRA/PPARA heterodimer is required for PPARA transcriptional activity on fatty acid oxidation genes such as ACOX1 and the P450 system genes. Homodimer. Heterodimer with RARA; required for ligand- dependent retinoic acid receptor transcriptional activity. Heterodimer with PPARA (via the leucine-like zipper in the LBD); the interaction is required for PPARA transcriptional activity. Also heterodimerizes with PPARG. Interacts with NCOA3 and NCOA6 coactivators. Interacts with FAM120B. Interacts with PELP1, SENP6, SFPQ, DNTTIP2 and RNF8. Interacts (via the DNA binding domain) with HCV core protein; the interaction enhances the transcriptional activities of the RXRA/RARA and the RXRA/PPARA heterodimers. Interacts with PRMT2. Interacts with ASXL1 and NCOA1. Highly expressed in liver, also found in lung, kidney and heart. Belongs to the nuclear hormone receptor family. NR2 subfamily.

Protein type: DNA-binding; Motility/polarity/chemotaxis; Nuclear receptor

Cellular Component: axon; nuclear chromatin; nucleus; receptor complex

Molecular Function: chromatin DNA binding; DNA binding; double-stranded DNA binding; enzyme binding; ligand-dependent nuclear receptor activity; protein binding; protein complex binding; protein domain specific binding; protein heterodimerization activity; retinoic acid receptor binding; retinoid-X receptor activity; sequence-specific DNA binding; transcription factor activity; transcription factor binding; vitamin D receptor binding

Biological Process: camera-type eye development; cardiac muscle cell differentiation; cardiac muscle cell proliferation; embryo implantation; heart development; heart morphogenesis; in utero embryonic development; maternal placenta development; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; placenta development; positive regulation of apoptosis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of translational initiation by iron; protein homotetramerization; regulation of myelination; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; response to glucocorticoid stimulus; response to retinoic acid; retinoic acid receptor signaling pathway; ventricular cardiac muscle cell differentiation; ventricular cardiac muscle morphogenesis; virus-host interaction
 Rxra ELISA Kit
 Rxra Recombinant
 Rxra Antibody
 Nr2b1 ELISA Kit
 Nr2b1 Recombinant
 Nr2b1 Antibody
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Retinoic acid receptor RXR-alpha-A

 Retinoic acid receptor RXR-alpha-A ELISA Kit
 Retinoic acid receptor RXR-alpha-A Recombinant
 Retinoic acid receptor RXR-alpha-A Antibody
Also known as Retinoic acid receptor RXR-alpha-A (Nuclear receptor subfamily 2 group B member 1-A) (RXRalpha-B) (Retinoid X receptor alpha-A).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodim
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ers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for rxrs is 9-cis retinoic acid ().
 rxraa ELISA Kit
 rxraa Recombinant
 rxraa Antibody
 nr2b1a ELISA Kit
 nr2b1a Recombinant
 nr2b1a Antibody
Table BarTOPTable Bar
 

Retinoic acid receptor RXR-alpha-B

 Retinoic acid receptor RXR-alpha-B ELISA Kit
 Retinoic acid receptor RXR-alpha-B Recombinant
 Retinoic acid receptor RXR-alpha-B Antibody
Also known as Retinoic acid receptor RXR-alpha-B (Nuclear receptor subfamily 2 group B member 1-B) (Retinoid X receptor alpha-B).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for this rxr is 9-cis retinoic acid ().
 rxrab ELISA Kit
 rxrab Recombinant
 rxrab Antibody
 nr2b1b ELISA Kit
 nr2b1b Recombinant
 nr2b1b Antibody
 rxra ELISA Kit
 rxra Recombinant
 rxra Antibody
 rxrg ELISA Kit
 rxrg Recombinant
 rxrg Antibody
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Retinoic acid receptor RXR-beta

 Retinoic acid receptor RXR-beta ELISA Kit
 Retinoic acid receptor RXR-beta Recombinant
 Retinoic acid receptor RXR-beta Antibody
Also known as Retinoic acid receptor RXR-beta (MHC class I regulatory element-binding protein H-2RIIBP) (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta).
RXRB: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various
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biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. Specifically binds 9-cis retinoic acid (9C-RA). Homodimer. Heterodimer with a RAR molecule. Binds DNA preferentially as a RAR/RXR heterodimer. Expressed in a variety of tumor cell lines. Belongs to the nuclear hormone receptor family. NR2 subfamily.

Protein type: DNA-binding; Nuclear receptor

Cellular Component: nucleus

Molecular Function: ligand-dependent nuclear receptor activity; protein binding; protein heterodimerization activity; protein homodimerization activity; retinoic acid receptor binding; retinoid-X receptor activity; sequence-specific DNA binding; thyroid hormone receptor binding; thyroid hormone receptor coactivator activity; vitamin D receptor binding

Biological Process: cardiac muscle cell proliferation; in utero embryonic development; maternal placenta development; positive regulation of transcription from RNA polymerase II promoter; regulation of myelination; retinoic acid receptor signaling pathway; ventricular cardiac muscle cell differentiation
 Rxrb ELISA Kit
 Rxrb Recombinant
 Rxrb Antibody
 Nr2b2 ELISA Kit
 Nr2b2 Recombinant
 Nr2b2 Antibody
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Retinoic acid receptor RXR-beta-A

 Retinoic acid receptor RXR-beta-A ELISA Kit
 Retinoic acid receptor RXR-beta-A Recombinant
 Retinoic acid receptor RXR-beta-A Antibody
Also known as Retinoic acid receptor RXR-beta-A (Nuclear receptor subfamily 2 group B member 2-A) (Retinoid X receptor beta-A).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for rxrs is 9-cis retinoic acid ().
 rxrba ELISA Kit
 rxrba Recombinant
 rxrba Antibody
 nr2b2a ELISA Kit
 nr2b2a Recombinant
 nr2b2a Antibody
 rxrb ELISA Kit
 rxrb Recombinant
 rxrb Antibody
 rxre ELISA Kit
 rxre Recombinant
 rxre Antibody
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Retinoic acid receptor RXR-beta-B

 Retinoic acid receptor RXR-beta-B ELISA Kit
 Retinoic acid receptor RXR-beta-B Recombinant
 Retinoic acid receptor RXR-beta-B Antibody
Also known as Retinoic acid receptor RXR-beta-B (Nuclear receptor subfamily 2 group B member 2-B) (Retinoic acid receptor RXR-delta) (Retinoid X receptor beta-B) (Retinoid X receptor delta).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for rxrs is 9-ci
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s retinoic acid ().
 rxrbb ELISA Kit
 rxrbb Recombinant
 rxrbb Antibody
 nr2b2b ELISA Kit
 nr2b2b Recombinant
 nr2b2b Antibody
 rxrd ELISA Kit
 rxrd Recombinant
 rxrd Antibody
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Retinoic acid receptor RXR-gamma

 Retinoic acid receptor RXR-gamma ELISA Kit
 Retinoic acid receptor RXR-gamma Recombinant
 Retinoic acid receptor RXR-gamma Antibody
Also known as Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the ret
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inoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid ().
 RXRG ELISA Kit
 RXRG Recombinant
 RXRG Antibody
 NR2B3 ELISA Kit
 NR2B3 Recombinant
 NR2B3 Antibody
Table BarTOPTable Bar
 

Retinoic acid receptor RXR-gamma-A

 Retinoic acid receptor RXR-gamma-A ELISA Kit
 Retinoic acid receptor RXR-gamma-A Recombinant
 Retinoic acid receptor RXR-gamma-A Antibody
Also known as Retinoic acid receptor RXR-gamma-A (Nuclear receptor subfamily 2 group B member 3-A) (Retinoic acid receptor RXR-alpha) (Retinoid X receptor alpha) (Retinoid X receptor gamma-A).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for rxrs is 9-
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cis retinoic acid ().
 rxrga ELISA Kit
 rxrga Recombinant
 rxrga Antibody
 nr2b1 ELISA Kit
 nr2b1 Recombinant
 nr2b1 Antibody
 nr2b3a ELISA Kit
 nr2b3a Recombinant
 nr2b3a Antibody
 rxr ELISA Kit
 rxr Recombinant
 rxr Antibody
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Retinoic acid receptor RXR-gamma-B

 Retinoic acid receptor RXR-gamma-B ELISA Kit
 Retinoic acid receptor RXR-gamma-B Recombinant
 Retinoic acid receptor RXR-gamma-B Antibody
Also known as Retinoic acid receptor RXR-gamma-B (Nuclear receptor subfamily 2 group B member 3-B) (Retinoid X receptor gamma-B).
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for rxrs is 9-cis retinoic acid ().
 rxrgb ELISA Kit
 rxrgb Recombinant
 rxrgb Antibody
 nr3b3b ELISA Kit
 nr3b3b Recombinant
 nr3b3b Antibody
 si:ch211-260g14.2 ELISA Kit
 si:ch211-260g14.2 Recombinant
 si:ch211-260g14.2 Antibody
 zgc:92183 ELISA Kit
 zgc:92183 Recombinant
 zgc:92183 Antibody
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