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RING finger and CHY zinc finger domain-containing protein

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Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.

Below are the list of possible RING finger and CHY zinc finger domain-containing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

RING finger and CHY zinc finger domain-containing protein 1

 RING finger and CHY zinc finger domain-containing protein 1 ELISA Kit
 RING finger and CHY zinc finger domain-containing protein 1 Recombinant
 RING finger and CHY zinc finger domain-containing protein 1 Antibody
Also known as RING finger and CHY zinc finger domain-containing protein 1 (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING finger protein 199) (Zinc finger protein 363) (p53.
RCHY1: Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, HDAC1 and p27Kip1. Preferentially acts on tetrameric p53/TP53. Contributes to the regulation of p27Kip1 and p53/TP53 levels, and thereby contributes to the regulation of the cell cycle progression. Increases AR transcription fa
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ctor activity. Monomer and homodimer. Interacts with AR, p53/TP53, MDM2, HDAC1, KAT5, PLAG1, PLAGL2, p27Kip1, COPE, UBE2D2 and GORAB/NTKLBP1. Up-regulated during the S phase of the cell cycle. Expressed at low levels during G phase. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.-; EC 6.3.2.19; Nuclear receptor co-regulator; Ubiquitin conjugating system; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 4q21.1

Cellular Component: cytoplasm; nucleoplasm; nucleus; ubiquitin ligase complex

Molecular Function: p53 binding; protein binding; protein homodimerization activity; ubiquitin-protein ligase activity; zinc ion binding

Biological Process: positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein ubiquitination; protein ubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process
 RCHY1 ELISA Kit
 RCHY1 Recombinant
 RCHY1 Antibody
 ARNIP ELISA Kit
 ARNIP Recombinant
 ARNIP Antibody
 CHIMP ELISA Kit
 CHIMP Recombinant
 CHIMP Antibody
 PIRH2 ELISA Kit
 PIRH2 Recombinant
 PIRH2 Antibody
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