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RNA polymerase-associated protein

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The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. Also has a role in transcription-coupled histone modification. Important for TATA site selection by TBP. Directly or indirectly regulates the DNA-binding properties of the TATA box-binding protein, and the relative activities of different TATA elements (By similarity).

Below are the list of possible RNA polymerase-associated protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

RNA polymerase-associated protein C651.09c

 RNA polymerase-associated protein C651.09c ELISA Kit
 RNA polymerase-associated protein C651.09c Recombinant
 RNA polymerase-associated protein C651.09c Antibody
Also known as RNA polymerase-associated protein C651.09c (Protein RTF1 homolog).
The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. Also has a role in transcription-coupled histone modification. Important for TATA site selection by TBP. Directly or indirectly regulates the DNA-binding p
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roperties of the TATA box-binding protein, and the relative activities of different TATA elements ().
 SPBC651.09c ELISA Kit
 SPBC651.09c Recombinant
 SPBC651.09c Antibody
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RNA polymerase-associated protein CTR9

 RNA polymerase-associated protein CTR9 ELISA Kit
 RNA polymerase-associated protein CTR9 Recombinant
 RNA polymerase-associated protein CTR9 Antibody
Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification (). Ctr-9 is required for epidermal microtubule organization during morphogenesis (PubMed:24721716).
 ctr-9 ELISA Kit
 ctr-9 Recombinant
 ctr-9 Antibody
 B0464.2 ELISA Kit
 B0464.2 Recombinant
 B0464.2 Antibody
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RNA polymerase-associated protein CTR9 homolog

 RNA polymerase-associated protein CTR9 homolog ELISA Kit
 RNA polymerase-associated protein CTR9 homolog Recombinant
 RNA polymerase-associated protein CTR9 homolog Antibody
Also known as RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).
Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) ().
 ctr9 ELISA Kit
 ctr9 Recombinant
 ctr9 Antibody
 sh2bp1 ELISA Kit
 sh2bp1 Recombinant
 sh2bp1 Antibody
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RNA polymerase-associated protein Gp33

 RNA polymerase-associated protein Gp33 ELISA Kit
 RNA polymerase-associated protein Gp33 Recombinant
 RNA polymerase-associated protein Gp33 Antibody
Binds to E.coli RNA polymerase and is required for transcription of late genes.
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RNA polymerase-associated protein LEO1

 RNA polymerase-associated protein LEO1 ELISA Kit
 RNA polymerase-associated protein LEO1 Recombinant
 RNA polymerase-associated protein LEO1 Antibody
The PAF1 complex is a multifunctional complex. May be involved in both initiation and elongation, histone methylation and RNA processing.
 leo1 ELISA Kit
 leo1 Recombinant
 leo1 Antibody
 DDB_G0286051 ELISA Kit
 DDB_G0286051 Recombinant
 DDB_G0286051 Antibody
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RNA polymerase-associated protein RapA

 RNA polymerase-associated protein RapA ELISA Kit
 RNA polymerase-associated protein RapA Recombinant
 RNA polymerase-associated protein RapA Antibody
Also known as RNA polymerase-associated protein RapA (ATP-dependent helicase HepA).
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription
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on linear DNA. Probably not involved in DNA repair.
 rapA ELISA Kit
 rapA Recombinant
 rapA Antibody
 AHA_0864 ELISA Kit
 AHA_0864 Recombinant
 AHA_0864 Antibody
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RNA polymerase-associated protein RTF1

 RNA polymerase-associated protein RTF1 ELISA Kit
 RNA polymerase-associated protein RTF1 Recombinant
 RNA polymerase-associated protein RTF1 Antibody
The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of NRD1 and NAB3 with RNA polymerase II. Also has a role in transcription-coupled histone modification. Required for activation of RAD6 ubiquitin conjugate and the BRE1 ubiquitin ligase which ubiquitinate 'Lys-126' histone H2B. Activates the SET1 histone methyltransferase complex for methylation of 'Lys-4' of histone H3 and for methylation of 'Ly
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s-73' of histone H3 by DOT1 and 'Lys-36' of histone H3 by SET2. Important for TATA site selection by TBP. Directly or indirectly regulates the DNA-binding properties of SPT15, the TATA box-binding protein, and the relative activities of different TATA elements.
 RTF1 ELISA Kit
 RTF1 Recombinant
 RTF1 Antibody
 CSL3 ELISA Kit
 CSL3 Recombinant
 CSL3 Antibody
 YGL244W ELISA Kit
 YGL244W Recombinant
 YGL244W Antibody
 HRA458 ELISA Kit
 HRA458 Recombinant
 HRA458 Antibody
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RNA polymerase-associated protein RTF1 homolog

 RNA polymerase-associated protein RTF1 homolog ELISA Kit
 RNA polymerase-associated protein RTF1 homolog Recombinant
 RNA polymerase-associated protein RTF1 homolog Antibody
RTF1: Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non- phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongati
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on, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of MLL1; it promotes leukemogenesis though association with MLL-rearranged oncoproteins, such as MLL-MLLT3/AF9 and MLL-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription. Binds single- stranded DNA. Required for maximal induction of heat-shock genes. Required for the trimethylation of histone H3 'Lys-4' (H3K4me3) on genes involved in stem cell pluripotency; this function is synergistic with CXXC1 indicative for an involvement of a SET1 complex.

Protein type: Transcription factor

Cellular Component: nucleolus

Molecular Function: single-stranded DNA binding

Biological Process: blastocyst growth; endodermal cell fate commitment; negative regulation of transcription from RNA polymerase II promoter; positive regulation of histone H3-K4 methylation; positive regulation of RNA elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; stem cell maintenance
 Rtf1 ELISA Kit
 Rtf1 Recombinant
 Rtf1 Antibody
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