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Sacsin

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Co-chaperone which acts as a regulator of the Hsp70 chaperone machinery and may be involved in the processing of other ataxia-linked proteins.

Below are the list of possible Sacsin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Sacsin

 Sacsin ELISA Kit
 Sacsin Recombinant
 Sacsin Antibody
Also known as Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29).
SACS: Co-chaperone which acts as a regulator of the Hsp70 chaperone machinery and may be involved in the processing of other ataxia-linked proteins. Defects in SACS are the cause of spastic ataxia Charlevoix-Saguenay type (SACS). It is a neurodegenerative disease characterized by early-onset cerebellar ataxia, spasticity, reti
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nal hypermyelination, pyramidal signs, and both axonal and demyelinating neuropathy with loss of sensory nerve conduction and reduced motor conduction velocities. Other features include dysarthria, distal muscle wasting, nystagmus, defect in conjugate pursuit ocular movements, retinal striation (from prominent retinal nerves) obscuring the retinal blood vessels in places, and the frequent presence of mitral valve prolapse. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Molecular Function: low-density lipoprotein receptor binding
 Sacs ELISA Kit
 Sacs Recombinant
 Sacs Antibody
 Kiaa0730 ELISA Kit
 Kiaa0730 Recombinant
 Kiaa0730 Antibody
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