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Salivary cystatin

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Inhibitor of cysteine proteinases. Inhibits host immune responses via its inhibition of host cathepsins. Contributes to the suppression of the host's immune response to tick salivary proteins and is important for successful feeding on hosts. Inhibits differentiation of host dendritic cells. Inhibits proliferation of host T-cells in response to antigen stimulus. Down-regulates TLR2-mediated host responses to infection by B.burgdorferi and the production of the chemokine CCL3 by host dendritic cells. Down-regulates host responses to infection by B.burgdorferi and the production of IFNB1 by host dendritic cells. Down-regulates IL1B production by host mast cells, and this then leads to impaired activation of IL1R1, resulting in decreased IL9 production. Inhibits host inflammatory reactions and recruitment of host neutrophils. Inhibits papain and cathepsin L (CTSL) (in vitro). Inhibits cathepsin S (CTSS) (in vitro). Inhibits CTSV and CTSC, but to a lesser degree (in vitro).

Below are the list of possible Salivary cystatin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Salivary cystatin-L

 Salivary cystatin-L ELISA Kit
 Salivary cystatin-L Recombinant
 Salivary cystatin-L Antibody
Also known as Salivary cystatin-L (Sialostatin L) (SialoL).
Inhibitor of cysteine proteinases. Inhibits host immune responses via its inhibition of host cathepsins. Contributes to the suppression of the host's immune response to tick salivary proteins and is important for successful feeding on hosts. Inhibits differentiation of host dendritic cells. Inhibits proliferation of host T-cells in res
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ponse to antigen stimulus. Down-regulates TLR2-mediated host responses to infection by B.burgdorferi and the production of the chemokine CCL3 by host dendritic cells. Down-regulates host responses to infection by B.burgdorferi and the production of IFNB1 by host dendritic cells. Down-regulates IL1B production by host mast cells, and this then leads to impaired activation of IL1R1, resulting in decreased IL9 production. Inhibits host inflammatory reactions and recruitment of host neutrophils. Inhibits papain and cathepsin L (CTSL) (in vitro). Inhibits cathepsin S (CTSS) (in vitro). Inhibits CTSV and CTSC, but to a lesser degree (in vitro).
 IscW_ISCW018603 ELISA Kit
 IscW_ISCW018603 Recombinant
 IscW_ISCW018603 Antibody
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Salivary cystatin-L2

 Salivary cystatin-L2 ELISA Kit
 Salivary cystatin-L2 Recombinant
 Salivary cystatin-L2 Antibody
Also known as Salivary cystatin-L2 (Sialostatin-L2).
Inhibitor of cysteine proteinases. Inhibits host immune responses, probably via its inhibition of host cathepsins. Contributes to the suppression of the host's immune response to tick salivary proteins and is important for successful feeding on hosts (PubMed:17698852). Down-regulates TLR2-mediated host responses to infection by B.burgdorferi
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and the production of chemokines CCL3 and CXCL10 by host dendritic cells (PubMed:25975355). Enhances infection by the tick-transmitted pathogen B.burgdorferi (in vitro) (PubMed:20545851). Inhibits host inflammatory responses to A.phagocytophilum infection (PubMed:24686067). Inhibits papain (in vitro) (PubMed:20545851). Inhibits cathepsin-L (CTSL) (in vitro) (PubMed:17698852, PubMed:20545851). Inhibits cathepsin-L2 (CTSV) (in vitro) (PubMed:17698852).
 IscW_ISCW018602 ELISA Kit
 IscW_ISCW018602 Recombinant
 IscW_ISCW018602 Antibody
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