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Scaffold attachment factor

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Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity).

Below are the list of possible Scaffold attachment factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Scaffold attachment factor B1

 Scaffold attachment factor B1 ELISA Kit
 Scaffold attachment factor B1 Recombinant
 Scaffold attachment factor B1 Antibody
Also known as Scaffold attachment factor B1 (SAF-B) (SAF-B1).
SAFB1: Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing. Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter
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and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter. Can inhibit cell proliferation.

Protein type: DNA-binding; Nuclear receptor co-regulator; RNA-binding

Cellular Component: nucleoplasm; nucleus

Molecular Function: chromatin binding; double-stranded DNA binding; protein binding; sequence-specific DNA binding

Biological Process: estrogen receptor signaling pathway; growth; hormone metabolic process; positive regulation of transcription from RNA polymerase II promoter; regulation of mRNA processing; regulation of transcription from RNA polymerase II promoter
 Safb ELISA Kit
 Safb Recombinant
 Safb Antibody
 Safb1 ELISA Kit
 Safb1 Recombinant
 Safb1 Antibody
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Scaffold attachment factor B2

 Scaffold attachment factor B2 ELISA Kit
 Scaffold attachment factor B2 Recombinant
 Scaffold attachment factor B2 Antibody
Also known as Scaffold attachment factor B2 (SAF-B2).
SAFB2: Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.

Protein type: Nuclear receptor co-regulator; RNA-binding

Cellular Component: intracellular membrane-bound organelle; nucleoplasm; nucleus

Molecular Function: double-stra
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nded DNA binding; sequence-specific DNA binding

Biological Process: regulation of mRNA processing; regulation of transcription from RNA polymerase II promoter; Sertoli cell differentiation
 Safb2 ELISA Kit
 Safb2 Recombinant
 Safb2 Antibody
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