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Schlafen family

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Interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis. Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner. Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides. The exact inhibition mechanism is unclear: may either sequesters tRNAs, prevents their maturation via post-transcriptional processing or accelerates their deacylation. Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA. May play a role in cell cycle arrest and/or induction of apoptosis in response to exogenously induced DNA damage.

Below are the list of possible Schlafen family products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Schlafen family member 11

 Schlafen family member 11 ELISA Kit
 Schlafen family member 11 Recombinant
 Schlafen family member 11 Antibody
SLFN11: Belongs to the Schlafen family.

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: tRNA binding

Biological Process: defense response to virus
 SLFN11 ELISA Kit
 SLFN11 Recombinant
 SLFN11 Antibody
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Schlafen family member 12

 Schlafen family member 12 ELISA Kit
 Schlafen family member 12 Recombinant
 Schlafen family member 12 Antibody
SLFN12: Belongs to the Schlafen family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 17q12
 SLFN12 ELISA Kit
 SLFN12 Recombinant
 SLFN12 Antibody
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Schlafen family member 12-like

 Schlafen family member 12-like ELISA Kit
 Schlafen family member 12-like Recombinant
 Schlafen family member 12-like Antibody
SLFN12L: Belongs to the Schlafen family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q12
 SLFN12L ELISA Kit
 SLFN12L Recombinant
 SLFN12L Antibody
 SLFN5 ELISA Kit
 SLFN5 Recombinant
 SLFN5 Antibody
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Schlafen family member 13

 Schlafen family member 13 ELISA Kit
 Schlafen family member 13 Recombinant
 Schlafen family member 13 Antibody
SLFN13: Belongs to the Schlafen family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: intracellular
 SLFN13 ELISA Kit
 SLFN13 Recombinant
 SLFN13 Antibody
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Schlafen family member 5

 Schlafen family member 5 ELISA Kit
 Schlafen family member 5 Recombinant
 Schlafen family member 5 Antibody
SLFN5: May have a role in hematopoietic cell differentiation. Belongs to the Schlafen family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q12
 SLFN5 ELISA Kit
 SLFN5 Recombinant
 SLFN5 Antibody
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