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SEC14-like protein

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May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.

Below are the list of possible SEC14-like protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

SEC14-like protein 1

 SEC14-like protein 1 ELISA Kit
 SEC14-like protein 1 Recombinant
 SEC14-like protein 1 Antibody
SEC14L1: belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system. Multiple alternatively spliced transcript variants have been found for this gene; some variants represent read-through transcripts that include exons from the upstream gene C17orf86. [prov
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ided by RefSeq, Feb 2011]

Cellular Component: cytoplasm; Golgi apparatus

Biological Process: choline transport
 Sec14l1 ELISA Kit
 Sec14l1 Recombinant
 Sec14l1 Antibody
 Kiaa4251 ELISA Kit
 Kiaa4251 Recombinant
 Kiaa4251 Antibody
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SEC14-like protein 2

 SEC14-like protein 2 ELISA Kit
 SEC14-like protein 2 Recombinant
 SEC14-like protein 2 Antibody
Also known as SEC14-like protein 2 (Alpha-tocopherol-associated protein) (TAP).
SEC14L2: Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association
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with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Cellular Component: cytosol

Molecular Function: enzyme activator activity; transferase activity, transferring alkyl or aryl (other than methyl) groups

Biological Process: positive regulation of cholesterol biosynthetic process
 Sec14l2 ELISA Kit
 Sec14l2 Recombinant
 Sec14l2 Antibody
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SEC14-like protein 3

 SEC14-like protein 3 ELISA Kit
 SEC14-like protein 3 Recombinant
 SEC14-like protein 3 Antibody
Also known as SEC14-like protein 3 (45 kDa secretory protein) (rsec45).
SEC14L3: Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids
 Sec14l3 ELISA Kit
 Sec14l3 Recombinant
 Sec14l3 Antibody
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SEC14-like protein 4

 SEC14-like protein 4 ELISA Kit
 SEC14-like protein 4 Recombinant
 SEC14-like protein 4 Antibody
SEC14L4: Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.

Protein type: Unknown function
 Sec14l4 ELISA Kit
 Sec14l4 Recombinant
 Sec14l4 Antibody
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SEC14-like protein 5

 SEC14-like protein 5 ELISA Kit
 SEC14-like protein 5 Recombinant
 SEC14-like protein 5 Antibody
 sec14l1 ELISA Kit
 sec14l1 Recombinant
 sec14l1 Antibody
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