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Secreted frizzled-related protein

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Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types.

Below are the list of possible Secreted frizzled-related protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Secreted frizzled-related protein 1

 Secreted frizzled-related protein 1 ELISA Kit
 Secreted frizzled-related protein 1 Recombinant
 Secreted frizzled-related protein 1 Antibody
Also known as Secreted frizzled-related protein 1 (CsFRP1) (sFRP-1).
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types.
 SFRP1 ELISA Kit
 SFRP1 Recombinant
 SFRP1 Antibody
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Secreted frizzled-related protein 2

 Secreted frizzled-related protein 2 ELISA Kit
 Secreted frizzled-related protein 2 Recombinant
 Secreted frizzled-related protein 2 Antibody
Also known as Secreted frizzled-related protein 2 (FRP-2) (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1).
SFRP2: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. Belongs to the secreted frizzled-related protein (sFRP) family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q31.3

Cellular Compon
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ent: extracellular matrix; extracellular space; integral to membrane

Molecular Function: fibronectin binding; G-protein coupled receptor activity; integrin binding; receptor agonist activity; Wnt receptor activity; Wnt-protein binding

Biological Process: cell-cell signaling; negative regulation of cell growth; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of epithelial cell proliferation; negative regulation of peptidyl-tyrosine phosphorylation; negative regulation of transcription, DNA-dependent; negative regulation of Wnt receptor signaling pathway; patterning of blood vessels; positive regulation of angiogenesis; positive regulation of apoptosis; positive regulation of cell adhesion mediated by integrin; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of fat cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription from RNA polymerase II promoter
 SFRP2 ELISA Kit
 SFRP2 Recombinant
 SFRP2 Antibody
 FRP2 ELISA Kit
 FRP2 Recombinant
 FRP2 Antibody
 SARP1 ELISA Kit
 SARP1 Recombinant
 SARP1 Antibody
 FKSG12 ELISA Kit
 FKSG12 Recombinant
 FKSG12 Antibody
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Secreted frizzled-related protein 3

 Secreted frizzled-related protein 3 ELISA Kit
 Secreted frizzled-related protein 3 Recombinant
 Secreted frizzled-related protein 3 Antibody
Also known as Secreted frizzled-related protein 3 (sFRP-3) (Frezzled) (Fritz) (Frizzled-related protein 1) (FrzB-1).
FRZB: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development. Defects in FRZB are associated with susceptibility to osteoarthritis type 1(OS1). Osteoarthritis is a degenerative dise
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ase of the joints characterized by degradation of the hyaline articular cartilage and remodeling of the subchondral bone with sclerosis. Clinical symptoms include pain and joint stiffness often leading to significant disability and joint replacement. Belongs to the secreted frizzled-related protein (sFRP) family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space; integral to membrane

Molecular Function: G-protein coupled receptor activity; protein binding; Wnt receptor activity; Wnt-protein binding

Biological Process: convergent extension involved in organogenesis; inner ear morphogenesis; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of Wnt receptor signaling pathway; neural crest cell differentiation; positive regulation of apoptosis; positive regulation of fat cell differentiation
 Frzb ELISA Kit
 Frzb Recombinant
 Frzb Antibody
 Fiz ELISA Kit
 Fiz Recombinant
 Fiz Antibody
 Fre ELISA Kit
 Fre Recombinant
 Fre Antibody
 Frzb1 ELISA Kit
 Frzb1 Recombinant
 Frzb1 Antibody
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Secreted frizzled-related protein 4

 Secreted frizzled-related protein 4 ELISA Kit
 Secreted frizzled-related protein 4 Recombinant
 Secreted frizzled-related protein 4 Antibody
Also known as Secreted frizzled-related protein 4 (sFRP-4).
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modul
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ation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake ().
 SFRP4 ELISA Kit
 SFRP4 Recombinant
 SFRP4 Antibody
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Secreted frizzled-related protein 5

 Secreted frizzled-related protein 5 ELISA Kit
 Secreted frizzled-related protein 5 Recombinant
 Secreted frizzled-related protein 5 Antibody
Also known as Secreted frizzled-related protein 5 (sFRP-5).
SFRP5: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. Belongs to the
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secreted frizzled-related protein (sFRP) family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: integral to membrane

Molecular Function: G-protein coupled receptor activity; Wnt receptor activity; Wnt-protein binding

Biological Process: convergent extension involved in axis elongation; digestive tract morphogenesis; negative regulation of cell proliferation; negative regulation of JNK activity; negative regulation of protein kinase B signaling cascade; negative regulation of transcription factor activity; negative regulation of Wnt receptor signaling pathway; Wnt receptor signaling pathway through beta-catenin
 Sfrp5 ELISA Kit
 Sfrp5 Recombinant
 Sfrp5 Antibody
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