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Semaphorin

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May function in growth cone guidance.

Below are the list of possible Semaphorin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Semaphorin-1A

 Semaphorin-1A ELISA Kit
 Semaphorin-1A Recombinant
 Semaphorin-1A Antibody
Also known as Semaphorin-1A (CeSema).
May function in growth cone guidance.
 smp-1 ELISA Kit
 smp-1 Recombinant
 smp-1 Antibody
 sema-1a ELISA Kit
 sema-1a Recombinant
 sema-1a Antibody
 Y54E5B.1 ELISA Kit
 Y54E5B.1 Recombinant
 Y54E5B.1 Antibody
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Semaphorin-2A

 Semaphorin-2A ELISA Kit
 Semaphorin-2A Recombinant
 Semaphorin-2A Antibody
Also known as Semaphorin-2A (Sema-2a) (Male abnormal protein 20).
Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays. Seems to control ce
>>>
ll-cell contact formation through two parallel pathways, one involving efn-4 and one involving plx-2 and unc-129. May also be involved in axon guidance ().
 mab-20 ELISA Kit
 mab-20 Recombinant
 mab-20 Antibody
 CBG22137 ELISA Kit
 CBG22137 Recombinant
 CBG22137 Antibody
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Semaphorin-3A

 Semaphorin-3A ELISA Kit
 Semaphorin-3A Recombinant
 Semaphorin-3A Antibody
Also known as Semaphorin-3A (Collapsin-1) (COLL-1).
Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to neuropilin.
 SEMA3A ELISA Kit
 SEMA3A Recombinant
 SEMA3A Antibody
 COLL1 ELISA Kit
 COLL1 Recombinant
 COLL1 Antibody
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Semaphorin-3aa

 Semaphorin-3aa ELISA Kit
 Semaphorin-3aa Recombinant
 Semaphorin-3aa Antibody
Also known as Semaphorin-3aa (Semaphorin-1A) (Semaphorin-Z1A) (Sema Z1A).
May influence outgrowth by a variety of growth cones including those of the posterior lateral line ganglion.
 sema3aa ELISA Kit
 sema3aa Recombinant
 sema3aa Antibody
 semaz1a ELISA Kit
 semaz1a Recombinant
 semaz1a Antibody
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Semaphorin-3ab

 Semaphorin-3ab ELISA Kit
 Semaphorin-3ab Recombinant
 Semaphorin-3ab Antibody
Also known as Semaphorin-3ab (Semaphorin-1B) (Semaphorin-Z1B) (Sema Z1B).
Might normally influence the midsegmental pathway choice of the ventrally extending motor axons by contributing to a repulsive domain in the posterior somite.
 sema3ab ELISA Kit
 sema3ab Recombinant
 sema3ab Antibody
 semaz1b ELISA Kit
 semaz1b Recombinant
 semaz1b Antibody
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Semaphorin-3B

 Semaphorin-3B ELISA Kit
 Semaphorin-3B Recombinant
 Semaphorin-3B Antibody
Also known as Semaphorin-3B (Sema A(V)) (Semaphorin-V) (Sema V).
SEMA3B: Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. Expressed abundantly but differentially in a variety of neural and nonneural tissues. Belongs to the semaphorin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: extracellular space
>>>
r>Molecular Function: chemorepellent activity; semaphorin receptor binding

Biological Process: axon guidance; cell-cell signaling; negative chemotaxis; negative regulation of axon extension involved in axon guidance; neural crest cell migration; positive regulation of cell migration
 SEMA3B ELISA Kit
 SEMA3B Recombinant
 SEMA3B Antibody
 SEMA5 ELISA Kit
 SEMA5 Recombinant
 SEMA5 Antibody
 SEMAA ELISA Kit
 SEMAA Recombinant
 SEMAA Antibody
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Semaphorin-3C

 Semaphorin-3C ELISA Kit
 Semaphorin-3C Recombinant
 Semaphorin-3C Antibody
Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance ().
 SEMA3C ELISA Kit
 SEMA3C Recombinant
 SEMA3C Antibody
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Semaphorin-3D

 Semaphorin-3D ELISA Kit
 Semaphorin-3D Recombinant
 Semaphorin-3D Antibody
SEMA3D: a secreted protein that induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space

Molecular Function: chemorepellent activity; semaphorin receptor binding

Biological Process
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: negative chemotaxis; negative regulation of axon extension involved in axon guidance; neural crest cell migration; positive regulation of cell migration
 Sema3d ELISA Kit
 Sema3d Recombinant
 Sema3d Antibody
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Semaphorin-3E

 Semaphorin-3E ELISA Kit
 Semaphorin-3E Recombinant
 Semaphorin-3E Antibody
SEMA3E: a secreted protein of the semaphorin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q21.11

Cellular Component: extracellular region

Molecular Function: chemorepellent activity; protein binding; semaphorin receptor binding

Biological Process: negative chemotaxis; negative regulation of angiogenesis; negative regulation of axon extension involved in axon guidance; negative regulation of cell-matrix adhesion; neural crest cell migration; patterning of blood vessels; positive regulation of cell migration;
>>>
regulation of cell shape; sprouting angiogenesis; synapse organization and biogenesis

Disease: Charge Syndrome
 SEMA3E ELISA Kit
 SEMA3E Recombinant
 SEMA3E Antibody
 KIAA0331 ELISA Kit
 KIAA0331 Recombinant
 KIAA0331 Antibody
 SEMAH ELISA Kit
 SEMAH Recombinant
 SEMAH Antibody
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Semaphorin-3F

 Semaphorin-3F ELISA Kit
 Semaphorin-3F Recombinant
 Semaphorin-3F Antibody
Also known as Semaphorin-3F (Sema III/F) (Semaphorin IV) (Sema IV).
SEMA3F: May play a role in cell motility and cell adhesion. Belongs to the semaphorin family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3p21.3

Molecular Function: chemorepellent activity; semaphorin receptor binding

Biologic
>>>
al Process: axon extension involved in axon guidance; axon guidance; negative regulation of axon extension involved in axon guidance; nerve development; neural crest cell migration; positive regulation of cell migration
 SEMA3F ELISA Kit
 SEMA3F Recombinant
 SEMA3F Antibody
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Semaphorin-3G

 Semaphorin-3G ELISA Kit
 Semaphorin-3G Recombinant
 Semaphorin-3G Antibody
SEMA3G: a secreted protein that has chemorepulsive activities for sympathetic axons. A high-affinity ligand of NRP2.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space

Molecular Function: chemorepellent activity; semaphorin receptor binding

Biological Process: negative chemotaxis; negative regulation of axon extension involved in ax
>>>
on guidance; neural crest cell migration; positive regulation of cell migration
 Sema3g ELISA Kit
 Sema3g Recombinant
 Sema3g Antibody
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Semaphorin-4A

 Semaphorin-4A ELISA Kit
 Semaphorin-4A Recombinant
 Semaphorin-4A Antibody
Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. Promotes phosphorylation of TIMD2. Inhibits angiogenesis. Promotes axon growth cone collapse. Inhibits axonal extension by providing local sign
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als to specify territories inaccessible for growing axons ().
 SEMA4A ELISA Kit
 SEMA4A Recombinant
 SEMA4A Antibody
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Semaphorin-4B

 Semaphorin-4B ELISA Kit
 Semaphorin-4B Recombinant
 Semaphorin-4B Antibody
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
 SEMA4B ELISA Kit
 SEMA4B Recombinant
 SEMA4B Antibody
 KIAA1745 ELISA Kit
 KIAA1745 Recombinant
 KIAA1745 Antibody
 SEMAC ELISA Kit
 SEMAC Recombinant
 SEMAC Antibody
 UNQ749/PRO1480 ELISA Kit
 UNQ749/PRO1480 Recombinant
 UNQ749/PRO1480 Antibody
Table BarTOPTable Bar
 

Semaphorin-4C

 Semaphorin-4C ELISA Kit
 Semaphorin-4C Recombinant
 Semaphorin-4C Antibody
SEMA4C: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. Belongs to the semaphorin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: extracellular space; membrane; postsy
>>>
naptic density; synaptic vesicle membrane

Molecular Function: chemorepellent activity; protein binding; semaphorin receptor binding

Biological Process: cell migration in hindbrain; muscle cell differentiation; negative chemotaxis; negative regulation of axon extension involved in axon guidance; neural crest cell migration; neural tube closure; positive regulation of cell migration; positive regulation of stress-activated MAPK cascade
 SEMA4C ELISA Kit
 SEMA4C Recombinant
 SEMA4C Antibody
 KIAA1739 ELISA Kit
 KIAA1739 Recombinant
 KIAA1739 Antibody
 SEMAI ELISA Kit
 SEMAI Recombinant
 SEMAI Antibody
 UNQ5855/PRO34487 ELISA Kit
 UNQ5855/PRO34487 Recombinant
 UNQ5855/PRO34487 Antibody
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Semaphorin-4D

 Semaphorin-4D ELISA Kit
 Semaphorin-4D Recombinant
 Semaphorin-4D Antibody
Also known as Semaphorin-4D (A8) (BB18) (GR3) (CD antigen CD100).
SEMA4D: a single-pass type I membrane protein that my play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q22.2

Cellular Component: extracellular space; integral to plasma membrane; plasma membrane

Molecular Function: chemorepellent activity; protein binding; receptor activity; receptor binding; semaphorin receptor binding;
>>>
transmembrane receptor activity

Biological Process: cell adhesion; immune response; negative chemotaxis; negative regulation of apoptosis; negative regulation of axon extension involved in axon guidance; negative regulation of cell adhesion; negative regulation of osteoblast differentiation; negative regulation of peptidyl-tyrosine phosphorylation; negative regulation of transcription from RNA polymerase II promoter; neural crest cell migration; positive regulation of cell migration; positive regulation of collateral sprouting; positive regulation of GTPase activity; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein amino acid phosphorylation; regulation of cell projection organization and biogenesis; regulation of cell shape; regulation of dendrite morphogenesis
 SEMA4D ELISA Kit
 SEMA4D Recombinant
 SEMA4D Antibody
 C9orf164 ELISA Kit
 C9orf164 Recombinant
 C9orf164 Antibody
 CD100 ELISA Kit
 CD100 Recombinant
 CD100 Antibody
 SEMAJ ELISA Kit
 SEMAJ Recombinant
 SEMAJ Antibody
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Semaphorin-4E

 Semaphorin-4E ELISA Kit
 Semaphorin-4E Recombinant
 Semaphorin-4E Antibody
Also known as Semaphorin-4E (Semaphorin-7) (Semaphorin-Z7) (Sema Z7).
 sema4e ELISA Kit
 sema4e Recombinant
 sema4e Antibody
 sema7 ELISA Kit
 sema7 Recombinant
 sema7 Antibody
 semaz7 ELISA Kit
 semaz7 Recombinant
 semaz7 Antibody
Table BarTOPTable Bar
 

Semaphorin-4F

 Semaphorin-4F ELISA Kit
 Semaphorin-4F Recombinant
 Semaphorin-4F Antibody
Also known as Semaphorin-4F (Semaphorin-M) (Sema M) (Semaphorin-W) (Sema W).
SEMA4F: a single-pass type I membrane protein that may play a role in axon guidance.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p13.1

Cellular Component: endoplasmic reticulum; extracellular space; integral to plasma membrane; membrane; plasma membrane

Molecular Function: chemorepellent activity; semaphorin receptor binding

Biological Process: axon guidance; cell-cell signaling; negative chemotaxis; negative regulation of axon
>>>
extension involved in axon guidance; nervous system development; neural crest cell migration; positive regulation of cell migration
 SEMA4F ELISA Kit
 SEMA4F Recombinant
 SEMA4F Antibody
 SEMAM ELISA Kit
 SEMAM Recombinant
 SEMAM Antibody
 SEMAW ELISA Kit
 SEMAW Recombinant
 SEMAW Antibody
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Semaphorin-4G

 Semaphorin-4G ELISA Kit
 Semaphorin-4G Recombinant
 Semaphorin-4G Antibody
SEMA4G: a single-pass type I membrane protein that may play a role in axon guidance.

Protein type: Membrane protein, integral

Cellular Component: extracellular space

Molecular Function: chemorepellent activity; protein binding; semaphorin receptor binding

Biological Process: negative chemotaxis; negative regulation of axon extension involved in axon guidance; neural cre
>>>
st cell migration; positive regulation of cell migration
 Sema4g ELISA Kit
 Sema4g Recombinant
 Sema4g Antibody
Table BarTOPTable Bar
 

Semaphorin-5A

 Semaphorin-5A ELISA Kit
 Semaphorin-5A Recombinant
 Semaphorin-5A Antibody
Also known as Semaphorin-5A (Semaphorin-F) (Sema F).
SEMA5A: a single-pass type I membrane protein that may act as positive axonal guidance cues.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 5p15.2

Cellular Component: integral to membrane; membrane; plasma membrane

Molecular Function: chemorepellent activity; heparan sulfate proteo
>>>
glycan binding; semaphorin receptor binding; syndecan binding

Biological Process: axonal fasciculation; blood vessel endothelial cell proliferation during sprouting angiogenesis; cell adhesion; cell-cell signaling; diencephalon development; negative regulation of axon extension involved in axon guidance; negative regulation of cell adhesion; nervous system development; neural crest cell migration; positive chemotaxis; positive regulation of actin filament depolymerization; positive regulation of angiogenesis; positive regulation of axon extension involved in axon guidance; positive regulation of cell migration; positive regulation of endothelial cell proliferation; positive regulation of protein kinase B signaling cascade
 SEMA5A ELISA Kit
 SEMA5A Recombinant
 SEMA5A Antibody
 SEMAF ELISA Kit
 SEMAF Recombinant
 SEMAF Antibody
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Semaphorin-5B

 Semaphorin-5B ELISA Kit
 Semaphorin-5B Recombinant
 Semaphorin-5B Antibody
SEMA5B: a single-pass type I membrane protein of the semaphorin family that may act as positive axonal guidance cues. Two alternatively spliced human isoforms have been described.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q21.1

Cellular Component: integral to membrane

Molecular Function: chemorepellent activity; semaphorin receptor binding

Biological Process: negative regulation of axon extension involved in axon guidance; neural crest cell migration; positive regulation of cell migration
 SEMA5B ELISA Kit
 SEMA5B Recombinant
 SEMA5B Antibody
 KIAA1445 ELISA Kit
 KIAA1445 Recombinant
 KIAA1445 Antibody
 SEMAG ELISA Kit
 SEMAG Recombinant
 SEMAG Antibody
 UNQ5867/PRO34001 ELISA Kit
 UNQ5867/PRO34001 Recombinant
 UNQ5867/PRO34001 Antibody
Table BarTOPTable Bar
 

Semaphorin-6A

 Semaphorin-6A ELISA Kit
 Semaphorin-6A Recombinant
 Semaphorin-6A Antibody
Also known as Semaphorin-6A (Semaphorin Q) (Sema Q) (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1).
SEMA6A: a single-pass type I membrane protein of the semaphorin family that can act as repulsive axon guidance cues. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation. Active as a homodimer
>>>
or oligomer. Interacts with EVL. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Cellular Component: integral to plasma membrane

Molecular Function: chemorepellent activity; protein binding; semaphorin receptor binding; transmembrane receptor activity

Biological Process: axon guidance; cell surface receptor linked signal transduction; centrosome localization; negative regulation of axon extension involved in axon guidance; neural crest cell migration; neuron migration
 Sema6a ELISA Kit
 Sema6a Recombinant
 Sema6a Antibody
 Semaq ELISA Kit
 Semaq Recombinant
 Semaq Antibody
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Semaphorin-6B

 Semaphorin-6B ELISA Kit
 Semaphorin-6B Recombinant
 Semaphorin-6B Antibody
Also known as Semaphorin-6B (Semaphorin VIB) (Sema VIB) (Semaphorin-N) (Sema N).
SEMA6B: May play a role in both peripheral and central nervous system development. Belongs to the semaphorin family.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: integral to plasma membrane

Molecular Function: chemorepellent activity; semaphorin receptor binding
>>>


Biological Process: negative regulation of axon extension involved in axon guidance; neural crest cell migration; positive regulation of cell migration
 Sema6b ELISA Kit
 Sema6b Recombinant
 Sema6b Antibody
 Seman ELISA Kit
 Seman Recombinant
 Seman Antibody
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Semaphorin-6C

 Semaphorin-6C ELISA Kit
 Semaphorin-6C Recombinant
 Semaphorin-6C Antibody
Also known as Semaphorin-6C (Semaphorin-Y) (Sema Y).
SEMA6C: a single-pass type I membrane protein that shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections. 3 isoforms of the human p
>>>
rotein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Cellular Component: integral to plasma membrane

Molecular Function: chemorepellent activity; semaphorin receptor binding

Biological Process: axon guidance; negative regulation of axon extension involved in axon guidance; neural crest cell migration; positive regulation of cell migration
 Sema6c ELISA Kit
 Sema6c Recombinant
 Sema6c Antibody
 Semay ELISA Kit
 Semay Recombinant
 Semay Antibody
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Semaphorin-6D

 Semaphorin-6D ELISA Kit
 Semaphorin-6D Recombinant
 Semaphorin-6D Antibody
SEMA6D: a single-pass type I membrane protein of the semaphorin family that shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections. Seven alternatively spliced human isoforms have been repo
>>>
rted. All are intrinsic membrane proteins except isoform 7, which is cytoplasmic.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q21.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: chemorepellent activity; semaphorin receptor binding

Biological Process: negative regulation of axon extension involved in axon guidance; neural crest cell migration; positive regulation of cell migration
 SEMA6D ELISA Kit
 SEMA6D Recombinant
 SEMA6D Antibody
 KIAA1479 ELISA Kit
 KIAA1479 Recombinant
 KIAA1479 Antibody
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Semaphorin-7A

 Semaphorin-7A ELISA Kit
 Semaphorin-7A Recombinant
 Semaphorin-7A Antibody
Also known as Semaphorin-7A (CDw108) (JMH blood group antigen) (John-Milton-Hargen human blood group Ag) (Semaphorin-K1) (Sema K1) (Semaphorin-L) (Sema L) (CD antigen CD108).
SEMA7A: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediat
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ed immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. Belongs to the semaphorin family.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 15q22.3-q23

Cellular Component: external side of plasma membrane; extracellular space; membrane; plasma membrane

Molecular Function: chemorepellent activity; integrin binding; protein binding; semaphorin receptor binding

Biological Process: immune response; integrin-mediated signaling pathway; negative chemotaxis; negative regulation of axon extension involved in axon guidance; neural crest cell migration; osteoblast differentiation; positive regulation of axon extension; positive regulation of cell migration; regulation of inflammatory response

Disease: Blood Group, John Milton Hagen System
 SEMA7A ELISA Kit
 SEMA7A Recombinant
 SEMA7A Antibody
 CD108 ELISA Kit
 CD108 Recombinant
 CD108 Antibody
 SEMAL ELISA Kit
 SEMAL Recombinant
 SEMAL Antibody
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