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Sentrin-specific protease

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Protease that deconjugates smo-1 from targeted proteins and may catalyze the processing of smo-1 to its mature form.

Below are the list of possible Sentrin-specific protease products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Sentrin-specific protease

 Sentrin-specific protease ELISA Kit
 Sentrin-specific protease Recombinant
 Sentrin-specific protease Antibody
Also known as Sentrin-specific protease (SUMO protease) (SuPr) (Ubiquitin-like protease).
Protease that deconjugates smo-1 from targeted proteins and may catalyze the processing of smo-1 to its mature form.
 ulp-1 ELISA Kit
 ulp-1 Recombinant
 ulp-1 Antibody
 T10F2.3 ELISA Kit
 T10F2.3 Recombinant
 T10F2.3 Antibody
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Sentrin-specific protease 1

 Sentrin-specific protease 1 ELISA Kit
 Sentrin-specific protease 1 Recombinant
 Sentrin-specific protease 1 Antibody
Also known as Sentrin-specific protease 1 (Sentrin/SUMO-specific protease SENP1).
SENP1: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional re
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pression activity. Belongs to the peptidase C48 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.22.68; Nuclear receptor co-regulator; Protease

Chromosomal Location of Human Ortholog: 12q13.1

Cellular Component: focal adhesion; nuclear membrane; nucleoplasm; nucleus

Molecular Function: endopeptidase activity; protein binding; SUMO-specific protease activity

Biological Process: caspase activation; positive regulation of transcription from RNA polymerase II promoter; protein desumoylation; protein sumoylation; proteolysis
 SENP1 ELISA Kit
 SENP1 Recombinant
 SENP1 Antibody
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Sentrin-specific protease 2

 Sentrin-specific protease 2 ELISA Kit
 Sentrin-specific protease 2 Recombinant
 Sentrin-specific protease 2 Antibody
Also known as Sentrin-specific protease 2 (Axam2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Sentrin/SUMO-specific protease SENP2).
SENP2: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulat
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e the Wnt pathway. Belongs to the peptidase C48 family.

Protein type: EC 3.4.22.68; Protease

Chromosomal Location of Human Ortholog: 3q27.2

Cellular Component: nuclear pore; nucleoplasm; PML body

Molecular Function: endopeptidase activity; protein binding; SUMO-specific protease activity

Biological Process: fat cell differentiation; negative regulation of protein ubiquitination; positive regulation of protein ubiquitination; protein destabilization; protein desumoylation; protein sumoylation
 SENP2 ELISA Kit
 SENP2 Recombinant
 SENP2 Antibody
 KIAA1331 ELISA Kit
 KIAA1331 Recombinant
 KIAA1331 Antibody
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Sentrin-specific protease 3

 Sentrin-specific protease 3 ELISA Kit
 Sentrin-specific protease 3 Recombinant
 Sentrin-specific protease 3 Antibody
Also known as Sentrin-specific protease 3 (SUMO-1-specific protease 3) (Sentrin/SUMO-specific protease SENP3).
SENP3: Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from
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nucleophosmin, NPM1. Binds to SUMO1 and SUMO3. Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components C17orf49, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with EP300, NPM1 and CDCA8. On oxidative stress, SENP3 degradation is blocked by inhibition of its ubiquitination, which stabilizes it as it accumulates in the nucleoplasm. Belongs to the peptidase C48 family.

Protein type: EC 3.4.22.68; Nucleolus; Protease; Ubiquitin-specific protease

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: nucleolus; nucleoplasm; nucleus

Molecular Function: endopeptidase activity; protein binding; SUMO-specific protease activity

Biological Process: protein desumoylation; rRNA processing
 SENP3 ELISA Kit
 SENP3 Recombinant
 SENP3 Antibody
 SSP3 ELISA Kit
 SSP3 Recombinant
 SSP3 Antibody
 SUSP3 ELISA Kit
 SUSP3 Recombinant
 SUSP3 Antibody
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Sentrin-specific protease 5

 Sentrin-specific protease 5 ELISA Kit
 Sentrin-specific protease 5 Recombinant
 Sentrin-specific protease 5 Antibody
Also known as Sentrin-specific protease 5 (Sentrin/SUMO-specific protease SENP5).
SENP5: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division. Belongs to the peptida
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se C48 family.

Protein type: EC 3.4.22.68; Nucleolus; Protease

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus

Molecular Function: endopeptidase activity; protein binding; SUMO-specific protease activity

Biological Process: protein desumoylation; protein sumoylation
 SENP5 ELISA Kit
 SENP5 Recombinant
 SENP5 Antibody
 FKSG45 ELISA Kit
 FKSG45 Recombinant
 FKSG45 Antibody
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Sentrin-specific protease 6

 Sentrin-specific protease 6 ELISA Kit
 Sentrin-specific protease 6 Recombinant
 Sentrin-specific protease 6 Antibody
Also known as Sentrin-specific protease 6 (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6).
SENP6: Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. Processes preferentially poly-SUMO2 and poly- SUMO3 chains, but does not efficiently process SUMO1, SUMO2 and SUMO3 precursors. Deconjugates SUMO1 from RXRA, leading to transcriptional activation. Involved in chromosome alignment and spindle assembly, by regulating the kinetochore CENPH-CENPI-CENPK complex. Desumoylates PML and CENPI, protecting them from degradation by the ubiquitin ligase RNF4, which
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targets polysumoylated proteins for proteasomal degradation. Desumoylates also RPA1, thus preventing recruitment of RAD51 to the DNA damage foci to initiate DNA repair through homologous recombination. Belongs to the peptidase C48 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.22.68; Protease

Chromosomal Location of Human Ortholog: 6q14.1

Cellular Component: cytoplasm; nucleoplasm

Molecular Function: protein binding; SUMO-specific protease activity

Biological Process: protein desumoylation
 SENP6 ELISA Kit
 SENP6 Recombinant
 SENP6 Antibody
 KIAA0797 ELISA Kit
 KIAA0797 Recombinant
 KIAA0797 Antibody
 SSP1 ELISA Kit
 SSP1 Recombinant
 SSP1 Antibody
 SUSP1 ELISA Kit
 SUSP1 Recombinant
 SUSP1 Antibody
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Sentrin-specific protease 7

 Sentrin-specific protease 7 ELISA Kit
 Sentrin-specific protease 7 Recombinant
 Sentrin-specific protease 7 Antibody
Also known as Sentrin-specific protease 7 (SUMO-1-specific protease 2) (Sentrin/SUMO-specific protease SENP7).
Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms ().
 SENP7 ELISA Kit
 SENP7 Recombinant
 SENP7 Antibody
 SUSP2 ELISA Kit
 SUSP2 Recombinant
 SUSP2 Antibody
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Sentrin-specific protease 8

 Sentrin-specific protease 8 ELISA Kit
 Sentrin-specific protease 8 Recombinant
 Sentrin-specific protease 8 Antibody
Also known as Sentrin-specific protease 8 (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8).
SENP8: Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53. Belongs to the peptidase C48 family.

Protein type: EC 3.4.22.68; Protease

Chromosomal Location of Human Ortholog: 15q23
 SENP8 ELISA Kit
 SENP8 Recombinant
 SENP8 Antibody
 DEN1 ELISA Kit
 DEN1 Recombinant
 DEN1 Antibody
 NEDP1 ELISA Kit
 NEDP1 Recombinant
 NEDP1 Antibody
 PRSC2 ELISA Kit
 PRSC2 Recombinant
 PRSC2 Antibody
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Proteins Root Name Listing
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