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Septin

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Septins are GTPases involved in cytokinesis that assemble early in the cell cycle as a patch at the incipient bud site and form a ring before bud emergence, which transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck. This collar persists until just before cytokinesis, when it splits into two rings that occupy opposite sides of the neck. The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Many proteins bind asymmetrically to the septin collar. The septin assembly is regulated by protein kinase GIN4. Septins are also involved in cell morphogenesis, chlamydospores morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization, and spore wall formation. CDC11 is required for the correct localization of SEC3 at bud tips and bud necks. Plays a key role in invasive growth and virulence.

Below are the list of possible Septin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Septin CDC11

 Septin CDC11 ELISA Kit
 Septin CDC11 Recombinant
 Septin CDC11 Antibody
Also known as Septin CDC11 (Cell division control protein 11).
Septins are GTPases involved in cytokinesis that assemble early in the cell cycle as a patch at the incipient bud site and form a ring before bud emergence, which transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck. This collar persists until just before cytokinesis, when it
>>>
splits into two rings that occupy opposite sides of the neck. The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Many proteins bind asymmetrically to the septin collar. The septin assembly is regulated by protein kinase GIN4. Septins are also involved in cell morphogenesis, chlamydospores morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization, and spore wall formation. CDC11 is required for the correct localization of SEC3 at bud tips and bud necks. Plays a key role in invasive growth and virulence.
 CDC11 ELISA Kit
 CDC11 Recombinant
 CDC11 Antibody
 CaO19.5691 ELISA Kit
 CaO19.5691 Recombinant
 CaO19.5691 Antibody
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Septin homolog spn1

 Septin homolog spn1 ELISA Kit
 Septin homolog spn1 Recombinant
 Septin homolog spn1 Antibody
Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells.
 spn1 ELISA Kit
 spn1 Recombinant
 spn1 Antibody
 SPAC4F10.11 ELISA Kit
 SPAC4F10.11 Recombinant
 SPAC4F10.11 Antibody
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Septin homolog spn2

 Septin homolog spn2 ELISA Kit
 Septin homolog spn2 Recombinant
 Septin homolog spn2 Antibody
Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells. Involved in the correct orientation of forespore membrane extension during sporulation. Binds phosphatidylinositol 4-phosphate.
 spn2 ELISA Kit
 spn2 Recombinant
 spn2 Antibody
 SPAC821.06 ELISA Kit
 SPAC821.06 Recombinant
 SPAC821.06 Antibody
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Septin homolog spn3

 Septin homolog spn3 ELISA Kit
 Septin homolog spn3 Recombinant
 Septin homolog spn3 Antibody
Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells.
 spn3 ELISA Kit
 spn3 Recombinant
 spn3 Antibody
 SPBC16A3.01 ELISA Kit
 SPBC16A3.01 Recombinant
 SPBC16A3.01 Antibody
 SPBC543.01c ELISA Kit
 SPBC543.01c Recombinant
 SPBC543.01c Antibody
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Septin homolog spn4

 Septin homolog spn4 ELISA Kit
 Septin homolog spn4 Recombinant
 Septin homolog spn4 Antibody
Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells.
 spn4 ELISA Kit
 spn4 Recombinant
 spn4 Antibody
 SPAC9G1.11c ELISA Kit
 SPAC9G1.11c Recombinant
 SPAC9G1.11c Antibody
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Septin homolog spn5

 Septin homolog spn5 ELISA Kit
 Septin homolog spn5 Recombinant
 Septin homolog spn5 Antibody
Also known as Septin homolog spn5 (Mei4-dependent protein 9) (Meiotic expression up-regulated protein 28).
Septin-like protein involved in the correct orientation of forespore membrane extension during sporulation.
 spn5 ELISA Kit
 spn5 Recombinant
 spn5 Antibody
 mde9 ELISA Kit
 mde9 Recombinant
 mde9 Antibody
 meu28 ELISA Kit
 meu28 Recombinant
 meu28 Antibody
 SPAC24C9.15c ELISA Kit
 SPAC24C9.15c Recombinant
 SPAC24C9.15c Antibody
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Septin homolog spn6

 Septin homolog spn6 ELISA Kit
 Septin homolog spn6 Recombinant
 Septin homolog spn6 Antibody
Septin-like protein involved in the correct orientation of forespore membrane extension during sporulation.
 spn6 ELISA Kit
 spn6 Recombinant
 spn6 Antibody
 SPCC188.12 ELISA Kit
 SPCC188.12 Recombinant
 SPCC188.12 Antibody
 SPCC584.09 ELISA Kit
 SPCC584.09 Recombinant
 SPCC584.09 Antibody
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Septin homolog spn7

 Septin homolog spn7 ELISA Kit
 Septin homolog spn7 Recombinant
 Septin homolog spn7 Antibody
Septin-like protein involved in the correct orientation of forespore membrane extension during sporulation. Binds phosphatidylinositol 4-phosphate.
 spn7 ELISA Kit
 spn7 Recombinant
 spn7 Antibody
 SPBC19F8.01c ELISA Kit
 SPBC19F8.01c Recombinant
 SPBC19F8.01c Antibody
 SPBC21.08c ELISA Kit
 SPBC21.08c Recombinant
 SPBC21.08c Antibody
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Septin-1

 Septin-1 ELISA Kit
 Septin-1 Recombinant
 Septin-1 Antibody
SEPT1: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential)

Protein type: Cell cycle regulation; Cytoskeletal; Hydrolase

Cellular Component: m
>>>
idbody

Biological Process: meiotic metaphase plate congression; spindle assembly involved in female meiosis
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Septin-10

 Septin-10 ELISA Kit
 Septin-10 Recombinant
 Septin-10 Antibody
Filament-forming cytoskeletal GTPase (). May play a role in cytokinesis (Potential).
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Septin-11

 Septin-11 ELISA Kit
 Septin-11 Recombinant
 Septin-11 Antibody
Filament-forming cytoskeletal GTPase (). May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in G
>>>
ABAergic synaptic connectivity ().
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Septin-12

 Septin-12 ELISA Kit
 Septin-12 Recombinant
 Septin-12 Antibody
SEPT12: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). Defects in SEPT12 are the cause of spermatogenic failure 10 (SPGF10). An infertility disorder caused by sperma
>>>
togenesis defects. It results in decreased sperm motility, concentration, and multiple sperm structural defects. The most prominent feature is a defective sperm annulus, a ring structure that demarcates the midpiece and the principal piece of the sperm tail. Belongs to the septin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Cytoskeletal; Hydrolase

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: cleavage furrow; microtubule cytoskeleton; midbody; perinuclear region of cytoplasm; spindle; stress fiber

Molecular Function: GDP binding; GTP binding; phosphoinositide binding; protein binding; protein homodimerization activity

Disease: Spermatogenic Failure 10
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Septin-14

 Septin-14 ELISA Kit
 Septin-14 Recombinant
 Septin-14 Antibody
SEPT14: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). Belongs to the septin family.

Protein type: Cell cycle regulation; Cytoskeletal; Hydrolase

Chrom
>>>
osomal Location of Human Ortholog: 7p11.2

Molecular Function: protein binding
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Septin-2

 Septin-2 ELISA Kit
 Septin-2 Recombinant
 Septin-2 Antibody
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated
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microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein ().
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Septin-2A

 Septin-2A ELISA Kit
 Septin-2A Recombinant
 Septin-2A Antibody
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium. Required for the progression through mitosis through regulation of chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements including convergent extension during gastrulation. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane protein
>>>
s between the cilia and plasma membranes. Controls cell shape and not polarization of cells during convergent extension ().
 sept2-A ELISA Kit
 sept2-A Recombinant
 sept2-A Antibody
 TNeu051p22.1 ELISA Kit
 TNeu051p22.1 Recombinant
 TNeu051p22.1 Antibody
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Septin-2B

 Septin-2B ELISA Kit
 Septin-2B Recombinant
 Septin-2B Antibody
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium. Required for the progression through mitosis through regulation of chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation (). Probably plays a role in ciliogenesis and collective
>>>
cell movements including convergent extension during gastrulation. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Controls cell shape and not polarization of cells during convergent extension.
 sept2-b ELISA Kit
 sept2-b Recombinant
 sept2-b Antibody
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Septin-4

 Septin-4 ELISA Kit
 Septin-4 Recombinant
 Septin-4 Antibody
Filament-forming cytoskeletal GTPase (). May play a role in cytokinesis (Potential). May play a role in platelet secretion ().
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Septin-5

 Septin-5 ELISA Kit
 Septin-5 Recombinant
 Septin-5 Antibody
Filament-forming cytoskeletal GTPase (). May play a role in cytokinesis (Potential). May play a role in platelet secretion ().
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Septin-6

 Septin-6 ELISA Kit
 Septin-6 Recombinant
 Septin-6 Antibody
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis ().
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Septin-7

 Septin-7 ELISA Kit
 Septin-7 Recombinant
 Septin-7 Antibody
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association
>>>
of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements ().
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Septin-8

 Septin-8 ELISA Kit
 Septin-8 Recombinant
 Septin-8 Antibody
Filament-forming cytoskeletal GTPase (). May play a role in cytokinesis (Potential). May play a role in platelet secretion ().
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Septin-8-A

 Septin-8-A ELISA Kit
 Septin-8-A Recombinant
 Septin-8-A Antibody
 sept8-a ELISA Kit
 sept8-a Recombinant
 sept8-a Antibody
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Septin-8-B

 Septin-8-B ELISA Kit
 Septin-8-B Recombinant
 Septin-8-B Antibody
 sept8b ELISA Kit
 sept8b Recombinant
 sept8b Antibody
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Septin-9

 Septin-9 ELISA Kit
 Septin-9 Recombinant
 Septin-9 Antibody
Also known as Septin-9 (Eighth septin) (Eseptin) (Septin-like protein) (SLP).
SEPT9: a member of a family of novel GTP binding proteins that have been implicated in cytokinesis and exocytosis. This
>>>
family include the cell division control proteins CDC3, CDC10, CDC11. Required for the completion of cytokinesis and suggest a role that is distinct from that of Nedd5.

Protein type: Cell cycle regulation; Cytoskeletal; Hydrolase

Cellular Component: actin cytoskeleton; axoneme; microtubule; perinuclear region of cytoplasm; stress fiber

Biological Process: protein heterooligomerization
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Proteins Root Name Listing
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