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Sex-determining transformer protein

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Plays a major role in controlling sexual phenotype .

Below are the list of possible Sex-determining transformer protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Sex-determining transformer protein 1

 Sex-determining transformer protein 1 ELISA Kit
 Sex-determining transformer protein 1 Recombinant
 Sex-determining transformer protein 1 Antibody
Also known as Sex-determining transformer protein 1 (Cbr-tra-1).
Plays a major role in controlling sexual phenotype (PubMed:18245372). Terminal global regulator in a well-characterized cascade of sex-determining genes (). Promotes female development (). Interacts with tra-2 to promote spermatogenesis (PubMed:11250902). Promotes spermatogenesis through the Tip60 HAT complex and by regulating the
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expression of genes, such as fog-3, required for male development (PubMed:24098152). Association with chromatin and at the fog-3 promoter requires wdr-5.1, and may also require wdr-5.2 (). With trr-1, activates the fog-3 gene to determine sperm/oocyte cell fate (PubMed:24098152). In hermaphrodites, binds to an intronic regulatory site in the ceh-30 gene, preventing ceh-30 transcription and thereby preventing survival of the CEM (cephalic male) sensory neurons ().
 tra-1 ELISA Kit
 tra-1 Recombinant
 tra-1 Antibody
 CBG13188 ELISA Kit
 CBG13188 Recombinant
 CBG13188 Antibody
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Sex-determining transformer protein 2

 Sex-determining transformer protein 2 ELISA Kit
 Sex-determining transformer protein 2 Recombinant
 Sex-determining transformer protein 2 Antibody
Also known as Sex-determining transformer protein 2 (Cbr-Tra-2A) (Cbr-tra-2).
Plays a major role in controlling sexual cell fates (PubMed:8889523, PubMed:11250902, PubMed:24098152). Promotes female development in XX animals where it sequesters one or more of the FEM proteins to the membrane thereby freeing the tra-1 protein (a putative transcription factor) to enter the nucleus and promote fema
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le development (). In XO animals it acts as a receptor for her-1 which prevents it from binding to FEM proteins thereby repressing the activity of tra-1 (). Negatively regulates male development when bound to fem-3 and is required together with tra-1 for promoting spermatogenesis (PubMed:12477393). Also required for feminizing tra-3 activity ().
 tra-2 ELISA Kit
 tra-2 Recombinant
 tra-2 Antibody
 CBG11194 ELISA Kit
 CBG11194 Recombinant
 CBG11194 Antibody
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