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SH3 domain-binding protein

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Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.

Below are the list of possible SH3 domain-binding protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

SH3 domain-binding protein 1

 SH3 domain-binding protein 1 ELISA Kit
 SH3 domain-binding protein 1 Recombinant
 SH3 domain-binding protein 1 Antibody
Also known as SH3 domain-binding protein 1 (3BP-1).
SH3BP1: Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac. 2 isoforms of the huma
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n protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; GAPs; GAPs, Rac/Rho

Molecular Function: SH3 domain binding
 Sh3bp1 ELISA Kit
 Sh3bp1 Recombinant
 Sh3bp1 Antibody
 3bp1 ELISA Kit
 3bp1 Recombinant
 3bp1 Antibody
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SH3 domain-binding protein 2

 SH3 domain-binding protein 2 ELISA Kit
 SH3 domain-binding protein 2 Recombinant
 SH3 domain-binding protein 2 Antibody
Also known as SH3 domain-binding protein 2 (3BP-2).
SH3BP2: an adaptor protein that binds differentially to the SH3 domains of certain proteins. Links the hemopoietic tyrosine kinase Fes to the cytoplasmic membrane in a phosphorylation dependent manner. Regulates FC-epsilon RI -mediated degranulation in rat basophilic leukemia RBL-2H3 cells. Expressed in a variety of tissues including lung, liv
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er, skeletal muscle, kidney and pancreas. Defects in 3BP2 are the cause of cherubism, an autosomal dominant inherited syndrome. Two differentially spliced isoforms have been described.

Protein type: Adaptor/scaffold

Molecular Function: protein binding; SH3 domain binding
 Sh3bp2 ELISA Kit
 Sh3bp2 Recombinant
 Sh3bp2 Antibody
 3bp2 ELISA Kit
 3bp2 Recombinant
 3bp2 Antibody
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SH3 domain-binding protein 4

 SH3 domain-binding protein 4 ELISA Kit
 SH3 domain-binding protein 4 Recombinant
 SH3 domain-binding protein 4 Antibody
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its
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activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy ().
 sh3bp4 ELISA Kit
 sh3bp4 Recombinant
 sh3bp4 Antibody
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SH3 domain-binding protein 4-A

 SH3 domain-binding protein 4-A ELISA Kit
 SH3 domain-binding protein 4-A Recombinant
 SH3 domain-binding protein 4-A Antibody
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy ().
 sh3bp4a ELISA Kit
 sh3bp4a Recombinant
 sh3bp4a Antibody
 sh3bp4 ELISA Kit
 sh3bp4 Recombinant
 sh3bp4 Antibody
 si:dkey-110p14.1 ELISA Kit
 si:dkey-110p14.1 Recombinant
 si:dkey-110p14.1 Antibody
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SH3 domain-binding protein 4-B

 SH3 domain-binding protein 4-B ELISA Kit
 SH3 domain-binding protein 4-B Recombinant
 SH3 domain-binding protein 4-B Antibody
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its
>>>
activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy ().
 sh3bp4-b ELISA Kit
 sh3bp4-b Recombinant
 sh3bp4-b Antibody
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SH3 domain-binding protein 5

 SH3 domain-binding protein 5 ELISA Kit
 SH3 domain-binding protein 5 Recombinant
 SH3 domain-binding protein 5 Antibody
Also known as SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK).
SH3BP5: Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. Belongs to the SH3BP5 family. 2 isoforms of the human protein are prod
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uced by alternative splicing.

Cellular Component: cytoplasm; mitochondrion

Molecular Function: protein kinase inhibitor activity; SH3 domain binding

Biological Process: negative regulation of protein kinase activity
 Sh3bp5 ELISA Kit
 Sh3bp5 Recombinant
 Sh3bp5 Antibody
 Sab ELISA Kit
 Sab Recombinant
 Sab Antibody
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SH3 domain-binding protein 5 homolog

 SH3 domain-binding protein 5 homolog ELISA Kit
 SH3 domain-binding protein 5 homolog Recombinant
 SH3 domain-binding protein 5 homolog Antibody
Also known as SH3 domain-binding protein 5 homolog (Protein parcase).
 pcs ELISA Kit
 pcs Recombinant
 pcs Antibody
 CG7761 ELISA Kit
 CG7761 Recombinant
 CG7761 Antibody
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SH3 domain-binding protein 5-like

 SH3 domain-binding protein 5-like ELISA Kit
 SH3 domain-binding protein 5-like Recombinant
 SH3 domain-binding protein 5-like Antibody
Also known as SH3 domain-binding protein 5-like (SH3BP-5-like).
 SH3BP5L ELISA Kit
 SH3BP5L Recombinant
 SH3BP5L Antibody
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Proteins Root Name Listing
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