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Short stature homeobox protein

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Controls fundamental aspects of growth and development.

Below are the list of possible Short stature homeobox protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Short stature homeobox protein

 Short stature homeobox protein ELISA Kit
 Short stature homeobox protein Recombinant
 Short stature homeobox protein Antibody
Also known as Short stature homeobox protein (Pseudoautosomal homeobox-containing osteogenic protein) (Short stature homeobox-containing protein).
SHOX: Controls fundamental aspects of growth and development. Defects in SHOX are the cause of Leri-Weill dyschondrosteosis (LWD). LWD is a dominantly inherited skeletal dysplasia characterized by moderate short stature predominantly because of short
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mesomelic limb segments. It is often associated with the Madelung deformity of the wrist, comprising bowing of the radius and dorsal dislocation of the distal ulna. Defects in SHOX are a cause of Langer mesomelic dysplasia (LMD). LMD is an autosomal recessive rare skeletal dysplasia characterized by severe short stature owing to shortening and maldevelopment of the mesomelic and rhizomelic segments of the limbs. Associated malformations are rarely reported and intellect is normal in all affected subjects reported to date. Defects in SHOX are a cause of idiopathic short stature (ISS). Idiopathic short stature is usually defined as a height below the third percentile for chronological age or minus 2 standard deviations of national height standards in the absence of specific causative disorders. Belongs to the paired homeobox family. Bicoid subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: Xp22.33;Yp11.3

Molecular Function: protein binding; transcription factor activity

Biological Process: skeletal development; transcription from RNA polymerase II promoter

Disease: Langer Mesomelic Dysplasia; Leri-weill Dyschondrosteosis; Short Stature, Idiopathic, Autosomal; Short Stature, Idiopathic, X-linked
 SHOX ELISA Kit
 SHOX Recombinant
 SHOX Antibody
 PHOG ELISA Kit
 PHOG Recombinant
 PHOG Antibody
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Short stature homeobox protein 2

 Short stature homeobox protein 2 ELISA Kit
 Short stature homeobox protein 2 Recombinant
 Short stature homeobox protein 2 Antibody
Also known as Short stature homeobox protein 2 (Homeobox protein Og12X) (OG-12) (Paired family homeodomain protein Prx3).
SHOX2: May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation. Belongs to the paired homeobox family. Bicoid subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Biological Process: chondrocyte development; chondrocyte differentiation; embryonic digestive tract morphogenesis; embryonic foreli
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mb morphogenesis; embryonic limb morphogenesis; embryonic morphogenesis; negative regulation of transcription from RNA polymerase II promoter; osteoblast differentiation; positive regulation of axonogenesis; positive regulation of mesenchymal cell proliferation; positive regulation of skeletal muscle fiber development; positive regulation of smoothened signaling pathway; positive regulation of transcription from RNA polymerase II promoter; regulation of chondrocyte differentiation
 Shox2 ELISA Kit
 Shox2 Recombinant
 Shox2 Antibody
 Og12x ELISA Kit
 Og12x Recombinant
 Og12x Antibody
 Prx3 ELISA Kit
 Prx3 Recombinant
 Prx3 Antibody
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