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Sialate O-acetylesterase

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Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid.

Below are the list of possible Sialate O-acetylesterase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Sialate O-acetylesterase

 Sialate O-acetylesterase ELISA Kit
 Sialate O-acetylesterase Recombinant
 Sialate O-acetylesterase Antibody
Also known as Sialate O-acetylesterase (H-Lse) (Sialic acid-specific 9-O-acetylesterase).
SIAE: Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Defects in SIAE are a cause of autoimmune disease type 6 (AIS6). Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheuma
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toid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.1.53; Hydrolase; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q24

Cellular Component: extracellular space

Molecular Function: sialate O-acetylesterase activity

Biological Process: carbohydrate metabolic process; regulation of immune system process

Disease: Autoimmune Disease, Susceptibility To, 6
 SIAE ELISA Kit
 SIAE Recombinant
 SIAE Antibody
 YSG2 ELISA Kit
 YSG2 Recombinant
 YSG2 Antibody
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