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Sialic acid-binding Ig-like lectin

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Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

Below are the list of possible Sialic acid-binding Ig-like lectin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Sialic acid-binding Ig-like lectin 10

 Sialic acid-binding Ig-like lectin 10 ELISA Kit
 Sialic acid-binding Ig-like lectin 10 Recombinant
 Sialic acid-binding Ig-like lectin 10 Antibody
Also known as Sialic acid-binding Ig-like lectin 10 (Siglec-10) (Siglec-like protein 2).
Siglec-10: a cell surface protein belonging to the immunoglobulin superfamily and the SIGLEC (sialic acid binding Ig-like lectin) family. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha2,3- or 2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLECs are typic
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ally expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Five alternatively spliced isoforms have been described.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3
 SIGLEC10 ELISA Kit
 SIGLEC10 Recombinant
 SIGLEC10 Antibody
 SLG2 ELISA Kit
 SLG2 Recombinant
 SLG2 Antibody
 UNQ477/PRO940 ELISA Kit
 UNQ477/PRO940 Recombinant
 UNQ477/PRO940 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 11

 Sialic acid-binding Ig-like lectin 11 ELISA Kit
 Sialic acid-binding Ig-like lectin 11 Recombinant
 Sialic acid-binding Ig-like lectin 11 Antibody
Also known as Sialic acid-binding Ig-like lectin 11 (Sialic acid-binding lectin 11) (Siglec-11).
SIGLEC11: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8- linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhib
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itory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.33
 SIGLEC11 ELISA Kit
 SIGLEC11 Recombinant
 SIGLEC11 Antibody
 UNQ9222/PRO28718 ELISA Kit
 UNQ9222/PRO28718 Recombinant
 UNQ9222/PRO28718 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 12

 Sialic acid-binding Ig-like lectin 12 ELISA Kit
 Sialic acid-binding Ig-like lectin 12 Recombinant
 Sialic acid-binding Ig-like lectin 12 Antibody
Also known as Sialic acid-binding Ig-like lectin 12 (Siglec-12) (Myeloid inhibitory siglec) (MIS) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (Sialic acid-binding Ig-like lectin E) (Siglec-E) (mSiglec-E) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).
SIGLEC7: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site
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may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro). Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Cellular Component: external side of plasma membrane; integral to membrane

Molecular Function: monosaccharide binding; receptor activity; receptor signaling protein activity; sialic acid binding

Biological Process: cell adhesion; negative regulation of inflammatory response; negative regulation of phagocytosis, engulfment
 Siglec12 ELISA Kit
 Siglec12 Recombinant
 Siglec12 Antibody
 Siglec5 ELISA Kit
 Siglec5 Recombinant
 Siglec5 Antibody
 Siglece ELISA Kit
 Siglece Recombinant
 Siglece Antibody
 Siglecl1 ELISA Kit
 Siglecl1 Recombinant
 Siglecl1 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 13

 Sialic acid-binding Ig-like lectin 13 ELISA Kit
 Sialic acid-binding Ig-like lectin 13 Recombinant
 Sialic acid-binding Ig-like lectin 13 Antibody
Also known as Sialic acid-binding Ig-like lectin 13 (Siglec-13).
Putative adhesion molecule that mediates sialic-acid dependent binding to cells.
 SIGLEC13 ELISA Kit
 SIGLEC13 Recombinant
 SIGLEC13 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 14

 Sialic acid-binding Ig-like lectin 14 ELISA Kit
 Sialic acid-binding Ig-like lectin 14 Recombinant
 Sialic acid-binding Ig-like lectin 14 Antibody
Also known as Sialic acid-binding Ig-like lectin 14 (Siglec-14).
SIGLEC14: Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. Interacts with TYROBP

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: plasma membrane >>>
>
Biological Process: innate immune response
 SIGLEC14 ELISA Kit
 SIGLEC14 Recombinant
 SIGLEC14 Antibody
 UNQ294/PRO333 ELISA Kit
 UNQ294/PRO333 Recombinant
 UNQ294/PRO333 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 15

 Sialic acid-binding Ig-like lectin 15 ELISA Kit
 Sialic acid-binding Ig-like lectin 15 Recombinant
 Sialic acid-binding Ig-like lectin 15 Antibody
Also known as Sialic acid-binding Ig-like lectin 15 (Siglec-15) (CD33 antigen-like 3).
SIGLEC15: Binds sialylated glycoproteins. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q12.3

Cellular Component: plasma membrane

Biological Process:
>>>
innate immune response
 SIGLEC15 ELISA Kit
 SIGLEC15 Recombinant
 SIGLEC15 Antibody
 CD33L3 ELISA Kit
 CD33L3 Recombinant
 CD33L3 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 16

 Sialic acid-binding Ig-like lectin 16 ELISA Kit
 Sialic acid-binding Ig-like lectin 16 Recombinant
 Sialic acid-binding Ig-like lectin 16 Antibody
Also known as Sialic acid-binding Ig-like lectin 16 (Siglec-16) (Siglec-P16).
Putative adhesion molecule that mediates sialic-acid dependent binding to cells.
 SIGLEC16 ELISA Kit
 SIGLEC16 Recombinant
 SIGLEC16 Antibody
 SIGLECP16 ELISA Kit
 SIGLECP16 Recombinant
 SIGLECP16 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 5

 Sialic acid-binding Ig-like lectin 5 ELISA Kit
 Sialic acid-binding Ig-like lectin 5 Recombinant
 Sialic acid-binding Ig-like lectin 5 Antibody
Also known as Sialic acid-binding Ig-like lectin 5 (Siglec-5) (CD33 antigen-like 2) (Obesity-binding protein 2) (OB-BP2) (OB-binding protein 2) (CD antigen CD170).
SIGLEC5: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

Protein type: Cell adhesion; Membrane protein, integral
>>>
>Chromosomal Location of Human Ortholog: 19q13.3

Molecular Function: protein binding
 SIGLEC5 ELISA Kit
 SIGLEC5 Recombinant
 SIGLEC5 Antibody
 CD33L2 ELISA Kit
 CD33L2 Recombinant
 CD33L2 Antibody
 OBBP2 ELISA Kit
 OBBP2 Recombinant
 OBBP2 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 6

 Sialic acid-binding Ig-like lectin 6 ELISA Kit
 Sialic acid-binding Ig-like lectin 6 Recombinant
 Sialic acid-binding Ig-like lectin 6 Antibody
Also known as Sialic acid-binding Ig-like lectin 6 (Siglec-6) (CD33 antigen-like 1) (CDw327) (Obesity-binding protein 1) (OB-BP1) (CD antigen CD327).
SIGLEC6: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, int
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egral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: integral to plasma membrane; membrane

Molecular Function: protein binding

Biological Process: cell-cell signaling
 SIGLEC6 ELISA Kit
 SIGLEC6 Recombinant
 SIGLEC6 Antibody
 CD33L ELISA Kit
 CD33L Recombinant
 CD33L Antibody
 CD33L1 ELISA Kit
 CD33L1 Recombinant
 CD33L1 Antibody
 OBBP1 ELISA Kit
 OBBP1 Recombinant
 OBBP1 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 7

 Sialic acid-binding Ig-like lectin 7 ELISA Kit
 Sialic acid-binding Ig-like lectin 7 Recombinant
 Sialic acid-binding Ig-like lectin 7 Antibody
Also known as Sialic acid-binding Ig-like lectin 7 (Siglec-7) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (CDw328) (D-siglec) (QA79 membrane protein) (p75) (CD antigen CD328).
SIGLEC7: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globo
>>>
side, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro). Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: receptor activity

Biological Process: regulation of immune response
 SIGLEC7 ELISA Kit
 SIGLEC7 Recombinant
 SIGLEC7 Antibody
 AIRM1 ELISA Kit
 AIRM1 Recombinant
 AIRM1 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 8

 Sialic acid-binding Ig-like lectin 8 ELISA Kit
 Sialic acid-binding Ig-like lectin 8 Recombinant
 Sialic acid-binding Ig-like lectin 8 Antibody
Also known as Sialic acid-binding Ig-like lectin 8 (Siglec-8) (Sialoadhesin family member 2) (SAF-2).
SIGLEC8: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surf
>>>
ace. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.33-q13.41

Molecular Function: protein binding; transmembrane receptor activity

Biological Process: signal transduction
 SIGLEC8 ELISA Kit
 SIGLEC8 Recombinant
 SIGLEC8 Antibody
 SAF2 ELISA Kit
 SAF2 Recombinant
 SAF2 Antibody
Table BarTOPTable Bar
 

Sialic acid-binding Ig-like lectin 9

 Sialic acid-binding Ig-like lectin 9 ELISA Kit
 Sialic acid-binding Ig-like lectin 9 Recombinant
 Sialic acid-binding Ig-like lectin 9 Antibody
Also known as Sialic acid-binding Ig-like lectin 9 (Siglec-9) (CDw329) (Protein FOAP-9) (CD antigen CD329).
Siglec-9: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Belongs to the immu
>>>
noglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.41

Cellular Component: plasma membrane

Biological Process: regulation of immune response
 SIGLEC9 ELISA Kit
 SIGLEC9 Recombinant
 SIGLEC9 Antibody
 UNQ668/PRO1302 ELISA Kit
 UNQ668/PRO1302 Recombinant
 UNQ668/PRO1302 Antibody
Table BarTOPTable Bar
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