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Signaling threshold-regulating transmembrane adapter

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Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.

Below are the list of possible Signaling threshold-regulating transmembrane adapter products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Signaling threshold-regulating transmembrane adapter 1

 Signaling threshold-regulating transmembrane adapter 1 ELISA Kit
 Signaling threshold-regulating transmembrane adapter 1 Recombinant
 Signaling threshold-regulating transmembrane adapter 1 Antibody
Also known as Signaling threshold-regulating transmembrane adapter 1 (SHP2-interacting transmembrane adapter protein) (Suppression-inducing transmembrane adapter 1).
SIT: a low molecular weight transmembrane adaptor protein. A disulfide-linked homodimer. Expressed in lymphocytes. Following phosphorylation by Src and possibly Tec kinases, recruits the SH2 domain-containing tyrosine phosphatase S
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HP2 via an immunoreceptor tyrosine-based inhibition motif (ITIM).

Protein type: Adaptor/scaffold; Membrane protein, integral

Cellular Component: plasma membrane

Molecular Function: kinase binding; SH2 domain binding

Biological Process: regulation of T cell activation; signal transduction
 Sit1 ELISA Kit
 Sit1 Recombinant
 Sit1 Antibody
 Sit ELISA Kit
 Sit Recombinant
 Sit Antibody
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