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Single-strand selective monofunctional uracil-DNA glycosylase

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Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.

Below are the list of possible Single-strand selective monofunctional uracil-DNA glycosylase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Single-strand selective monofunctional uracil DNA glycosylase

 Single-strand selective monofunctional uracil DNA glycosylase ELISA Kit
 Single-strand selective monofunctional uracil DNA glycosylase Recombinant
 Single-strand selective monofunctional uracil DNA glycosylase Antibody
Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil
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(hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.
 SMUG1 ELISA Kit
 SMUG1 Recombinant
 SMUG1 Antibody
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Single-strand selective monofunctional uracil-DNA glycosylase

 Single-strand selective monofunctional uracil-DNA glycosylase ELISA Kit
 Single-strand selective monofunctional uracil-DNA glycosylase Recombinant
 Single-strand selective monofunctional uracil-DNA glycosylase Antibody
involved in the repair of 5-formyluracil and other oxidized and deaminated base lesions [RGD, Feb 2006]
 Smug1 ELISA Kit
 Smug1 Recombinant
 Smug1 Antibody
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