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Slit homolog 1 protein

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Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.

Below are the list of possible Slit homolog 1 protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Slit homolog 1 protein

 Slit homolog 1 protein ELISA Kit
 Slit homolog 1 protein Recombinant
 Slit homolog 1 protein Antibody
Also known as Slit homolog 1 protein (Slit-1).
SLIT1: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for
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midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space; proteinaceous extracellular matrix

Molecular Function: heparan sulfate proteoglycan binding; heparin binding; receptor binding; Roundabout binding

Biological Process: axon extension involved in axon guidance; axon guidance; axonogenesis; dorsal/ventral axon guidance; establishment of nucleus localization; motor axon guidance; negative chemotaxis; negative regulation of axon extension involved in axon guidance; neurite morphogenesis; olfactory bulb development; regulation of axonogenesis; retinal ganglion cell axon guidance; tangential migration from the subventricular zone to the olfactory bulb; telencephalon cell migration
 Slit1 ELISA Kit
 Slit1 Recombinant
 Slit1 Antibody
 Kiaa0813 ELISA Kit
 Kiaa0813 Recombinant
 Kiaa0813 Antibody
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