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Small kinetochore-associated protein

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Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.

Below are the list of possible Small kinetochore-associated protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Small kinetochore-associated protein

 Small kinetochore-associated protein ELISA Kit
 Small kinetochore-associated protein Recombinant
 Small kinetochore-associated protein Antibody
Also known as Small kinetochore-associated protein (SKAP) (Kinetochore-localized astrin-binding protein) (Kinastrin) (Kinetochore-localized astrin/SPAG5-binding protein) (TRAF4-associated factor 1).
TRAF4AF1: Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore atta
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chments. 3 isoforms of the human protein are produced by alternative splicing.

Cellular Component: cytoplasm; kinetochore; microtubule cytoskeleton

Biological Process: chromosome segregation; mitotic sister chromatid segregation; regulation of attachment of spindle microtubules to kinetochore; spindle organization and biogenesis
 Knstrn ELISA Kit
 Knstrn Recombinant
 Knstrn Antibody
 Skap ELISA Kit
 Skap Recombinant
 Skap Antibody
 Traf4af1 ELISA Kit
 Traf4af1 Recombinant
 Traf4af1 Antibody
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