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Snaclec alboluxin

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Potent platelet activator that aggregates platelets via both GPIb (GP1BA/GP1BB) and GPVI (GP6). Alboluxin induces a tyrosine phosphorylation profile in platelets that resembles those produced by collagen and convulxin, involving the time dependent tyrosine phosphorylation of Fc receptor gamma chain (FCGR1A), phospholipase Cgamma2 (PLCG2), LAT and p72SYK. Inhibition of alpha-IIb/beta-3 reduces the aggregation response to alboluxin, as well as tyrosine phosphorylation of platelet proteins, showing that activation of alpha-IIb/beta-3 and binding of fibrinogen are involved in alboluxin-induced platelet aggregation and it is not simply agglutination.

Below are the list of possible Snaclec alboluxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Snaclec alboluxin subunit beta

 Snaclec alboluxin subunit beta ELISA Kit
 Snaclec alboluxin subunit beta Recombinant
 Snaclec alboluxin subunit beta Antibody
Potent platelet activator that aggregates platelets via both GPIb (GP1BA/GP1BB) and GPVI (GP6). Alboluxin induces a tyrosine phosphorylation profile in platelets that resembles those produced by colla
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gen and convulxin, involving the time dependent tyrosine phosphorylation of Fc receptor gamma chain (FCGR1A), phospholipase Cgamma2 (PLCG2), LAT and p72SYK. Inhibition of alpha-IIb/beta-3 reduces the aggregation response to alboluxin, as well as tyrosine phosphorylation of platelet proteins, showing that activation of alpha-IIb/beta-3 and binding of fibrinogen are involved in alboluxin-induced platelet aggregation and it is not simply agglutination.
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