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Sodium channel

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Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity).

Below are the list of possible Sodium channel products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Sodium channel subunit beta-1

 Sodium channel subunit beta-1 ELISA Kit
 Sodium channel subunit beta-1 Recombinant
 Sodium channel subunit beta-1 Antibody
Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons ().
 SCN1B ELISA Kit
 SCN1B Recombinant
 SCN1B Antibody
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Sodium channel subunit beta-2

 Sodium channel subunit beta-2 ELISA Kit
 Sodium channel subunit beta-2 Recombinant
 Sodium channel subunit beta-2 Antibody
Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier ().
 SCN2B ELISA Kit
 SCN2B Recombinant
 SCN2B Antibody
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Sodium channel subunit beta-3

 Sodium channel subunit beta-3 ELISA Kit
 Sodium channel subunit beta-3 Recombinant
 Sodium channel subunit beta-3 Antibody
Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons ().
 SCN3B ELISA Kit
 SCN3B Recombinant
 SCN3B Antibody
 QmoA-13657 ELISA Kit
 QmoA-13657 Recombinant
 QmoA-13657 Antibody
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Sodium channel subunit beta-4

 Sodium channel subunit beta-4 ELISA Kit
 Sodium channel subunit beta-4 Recombinant
 Sodium channel subunit beta-4 Antibody
SCN4B: Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Defects in SCN4B are the cause of long QT syndrome type 10 (LQT10). Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. Th
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ey cause syncope and sudden death in response to excercise or emotional stress. They can present with a sentinel event of sudden cardiac death in infancy. Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: intrinsic to plasma membrane; plasma membrane; voltage-gated sodium channel complex

Molecular Function: sodium channel regulator activity; voltage-gated sodium channel activity

Biological Process: cardiac muscle contraction; sodium ion transport
 Scn4b ELISA Kit
 Scn4b Recombinant
 Scn4b Antibody
 Gm1471 ELISA Kit
 Gm1471 Recombinant
 Gm1471 Antibody
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