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Sodium-dependent phosphate transport protein

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Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane.

Below are the list of possible Sodium-dependent phosphate transport protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Sodium-dependent phosphate transport protein 1

 Sodium-dependent phosphate transport protein 1 ELISA Kit
 Sodium-dependent phosphate transport protein 1 Recombinant
 Sodium-dependent phosphate transport protein 1 Antibody
Also known as Sodium-dependent phosphate transport protein 1 (Na(+)/PI cotransporter 1) (Na/Pi-4) (Renal Na(+)-dependent phosphate cotransporter 1) (Renal sodium-dependent phosphate transport protein 1) (Renal sodium-phosphate transport protein 1) (Sodium/phosphate cotransporter 1) (Solute carrier family 17 member 1).
SLC17A1: Important for the resorption of phosphate by the kidney. May be invo
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lved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 6p22.2

Cellular Component: integral to plasma membrane; membrane; plasma membrane

Molecular Function: sodium-dependent phosphate transmembrane transporter activity; sodium:phosphate symporter activity

Biological Process: ion transport; phosphate transport; urate metabolic process
 SLC17A1 ELISA Kit
 SLC17A1 Recombinant
 SLC17A1 Antibody
 NPT1 ELISA Kit
 NPT1 Recombinant
 NPT1 Antibody
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Sodium-dependent phosphate transport protein 2A

 Sodium-dependent phosphate transport protein 2A ELISA Kit
 Sodium-dependent phosphate transport protein 2A Recombinant
 Sodium-dependent phosphate transport protein 2A Antibody
Also known as Sodium-dependent phosphate transport protein 2A (Sodium-phosphate transport protein 2A) (Na(+)-dependent phosphate cotransporter 2A) (NaPi-3) (Sodium/phosphate cotransporter 2A) (Na(+)/Pi cotransporter 2A) (NaPi-2a) (Solute carrier family 34 member 1).
SLC34A1: May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx. Defects in SLC34A1 are the cause of hypophosphatemic nephrolithiasis/osteoporosis type 1 (NPHLOP1). Hypophosphatemia results from idiopathic renal phospha
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te loss. It contributes to the pathogenesis of hypophosphatemic urolithiasis (formation of urinary calculi) as well to that of hypophosphatemic osteoporosis (bone demineralization). Defects in SLC34A1 are the cause of Fanconi renotubular syndrome type 2 (FRTS2). It is a disease resulting from a generalized dysfunction of the proximal kidney tubule leading to decreased solute and water reabsorption. Patients have polydipsia and polyuria with phosphaturia, glycosuria and aminoaciduria. They may develop hypophosphatemic rickets or osteomalacia, acidosis and a tendency toward dehydration. Some eventually develop renal insufficiency. Belongs to the SLC34A transporter family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 5q35

Cellular Component: apical plasma membrane; brush border; brush border membrane; cytoplasm; plasma membrane; vesicle

Molecular Function: inorganic phosphate transmembrane transporter activity; protein binding; sodium-dependent phosphate transmembrane transporter activity; sodium:phosphate symporter activity

Biological Process: cellular phosphate ion homeostasis; cellular protein metabolic process; phosphate ion homeostasis; phosphate transport; response to cadmium ion; response to lead ion; response to mercury ion

Disease: Fanconi Renotubular Syndrome 2; Hypercalcemia, Infantile, 2; Nephrolithiasis/osteoporosis, Hypophosphatemic, 1
 SLC34A1 ELISA Kit
 SLC34A1 Recombinant
 SLC34A1 Antibody
 NPT2 ELISA Kit
 NPT2 Recombinant
 NPT2 Antibody
 SLC17A2 ELISA Kit
 SLC17A2 Recombinant
 SLC17A2 Antibody
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Sodium-dependent phosphate transport protein 2B

 Sodium-dependent phosphate transport protein 2B ELISA Kit
 Sodium-dependent phosphate transport protein 2B Recombinant
 Sodium-dependent phosphate transport protein 2B Antibody
Also known as Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi3b) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2).
SLC34A2: May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transpo
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rt protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli. Defects in SLC34A2 are a cause of pulmonary alveolar microlithiasis (PALM). Pulmonary alveolar microlithiasis is a rare disease characterized by the deposition of calcium phosphate microliths throughout the lungs. Most patients are asymptomatic for several years or even for decades and generally, the diagnosis is incidental to clinical investigations unrelated to the disease. Cases with early onset or rapid progression are rare. A 'sandstorm-appearing' chest roentgenogram is a typical diagnostic finding. The onset of this potentially lethal disease varies from the neonatal period to old age and the disease follows a long-term, progressive course, resulting in a slow deterioration of lung functions. Pulmonary alveolar microlithiasis is a recessive monogenic disease with full penetrance. A chromosomal aberration involving SLC34A2 is found in a non-small cell lung cancer cell line. Results in the formation of a SLC34A2-ROS1 chimeric protein that retains a constitutive kinase activity. Belongs to the SLC34A transporter family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 4p15.2

Cellular Component: apical plasma membrane; brush border; brush border membrane; cytoplasm; integral to membrane; plasma membrane; vesicle

Molecular Function: inorganic phosphate transmembrane transporter activity; phosphate binding; sodium ion binding; sodium-dependent phosphate transmembrane transporter activity; sodium:phosphate symporter activity

Biological Process: cellular phosphate ion homeostasis; cellular protein metabolic process; phosphate transport; response to estrogen stimulus

Disease: Pulmonary Alveolar Microlithiasis; Testicular Microlithiasis
 SLC34A2 ELISA Kit
 SLC34A2 Recombinant
 SLC34A2 Antibody
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Sodium-dependent phosphate transport protein 2C

 Sodium-dependent phosphate transport protein 2C ELISA Kit
 Sodium-dependent phosphate transport protein 2C Recombinant
 Sodium-dependent phosphate transport protein 2C Antibody
Also known as Sodium-dependent phosphate transport protein 2C (Sodium-phosphate transport protein 2C) (Na(+)-dependent phosphate cotransporter 2C) (Sodium/inorganic phosphate cotransporter IIC) (Sodium/phosphate cotransporter 2C) (Na(+)/Pi cotransporter 2C) (NaPi-2c) (Solute carrier family 34 member 3).
SLC34A3: May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx. Defects in SLC34A3 are the cause of hereditary hypophosphatemic rickets with hypercalciuria (HHRH). HHRH is an autos
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omal recessive form of hypophosphatemia characterized by reduced renal phosphate reabsorption and rickets. Increased serum levels of 1,25-dihydroxyvitamin D lead to increase in urinary calcium excretion. Belongs to the SLC34A transporter family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: apical plasma membrane; brush border; cytoplasm; plasma membrane; vesicle

Molecular Function: inorganic phosphate transmembrane transporter activity; sodium-dependent phosphate transmembrane transporter activity; sodium:phosphate symporter activity

Biological Process: cellular phosphate ion homeostasis; phosphate transport; sodium ion transport

Disease: Hypophosphatemic Rickets With Hypercalciuria, Hereditary
 SLC34A3 ELISA Kit
 SLC34A3 Recombinant
 SLC34A3 Antibody
 NPT2C ELISA Kit
 NPT2C Recombinant
 NPT2C Antibody
 NPTIIC ELISA Kit
 NPTIIC Recombinant
 NPTIIC Antibody
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Sodium-dependent phosphate transport protein 3

 Sodium-dependent phosphate transport protein 3 ELISA Kit
 Sodium-dependent phosphate transport protein 3 Recombinant
 Sodium-dependent phosphate transport protein 3 Antibody
Also known as Sodium-dependent phosphate transport protein 3 (Na(+)/PI cotransporter 3) (Sodium/phosphate cotransporter 3) (Solute carrier family 17 member 2).
SLC17A2: May be involved in actively transporting phosphate into cells via Na(+) cotransport. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. 2 isoforms of the human protein are produced by alternative sp
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licing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Cellular Component: integral to plasma membrane

Molecular Function: sodium-dependent phosphate transmembrane transporter activity; sodium:phosphate symporter activity
 Slc17a2 ELISA Kit
 Slc17a2 Recombinant
 Slc17a2 Antibody
 Npt3 ELISA Kit
 Npt3 Recombinant
 Npt3 Antibody
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Sodium-dependent phosphate transport protein 4

 Sodium-dependent phosphate transport protein 4 ELISA Kit
 Sodium-dependent phosphate transport protein 4 Recombinant
 Sodium-dependent phosphate transport protein 4 Antibody
Also known as Sodium-dependent phosphate transport protein 4 (Na(+)/PI cotransporter 4) (Sodium/phosphate cotransporter 4) (Solute carrier family 17 member 3).
SLC17A3: Isoform 2: voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate efflux t
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ransporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+) cotransport. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: apical plasma membrane; brush border membrane; cytoplasm; endoplasmic reticulum membrane; integral to plasma membrane; perinuclear region of cytoplasm; plasma membrane

Molecular Function: drug transporter activity; efflux transmembrane transporter activity; organic anion transmembrane transporter activity; sodium-dependent phosphate transmembrane transporter activity; sodium:phosphate symporter activity; toxin transporter activity; urate transmembrane transporter activity; voltage-gated anion channel activity

Biological Process: drug transport; glucose-6-phosphate transport; organic anion transport; phosphate transport; sodium ion transport; urate metabolic process; urate transport

Disease: Uric Acid Concentration, Serum, Quantitative Trait Locus 4
 SLC17A3 ELISA Kit
 SLC17A3 Recombinant
 SLC17A3 Antibody
 NPT4 ELISA Kit
 NPT4 Recombinant
 NPT4 Antibody
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