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Somatostatin receptor

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Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins (By similarity).

Below are the list of possible Somatostatin receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Somatostatin receptor type 1

 Somatostatin receptor type 1 ELISA Kit
 Somatostatin receptor type 1 Recombinant
 Somatostatin receptor type 1 Antibody
Also known as Somatostatin receptor type 1 (SS-1-R) (SS1-R) (SS1R).
Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na+/H+ exchanger via pertussis toxin insensitive G proteins ().
 SSTR1 ELISA Kit
 SSTR1 Recombinant
 SSTR1 Antibody
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Somatostatin receptor type 2

 Somatostatin receptor type 2 ELISA Kit
 Somatostatin receptor type 2 Recombinant
 Somatostatin receptor type 2 Antibody
Also known as Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R).
Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium
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channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization ().
 SSTR2 ELISA Kit
 SSTR2 Recombinant
 SSTR2 Antibody
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Somatostatin receptor type 3

 Somatostatin receptor type 3 ELISA Kit
 Somatostatin receptor type 3 Recombinant
 Somatostatin receptor type 3 Antibody
Also known as Somatostatin receptor type 3 (SS-3-R) (SS3-R) (SS3R) (SSR-28).
SSTR3: Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cell
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ular Component: cilium; cytoplasm; integral to plasma membrane; neuron projection; plasma membrane

Molecular Function: G-protein coupled receptor activity; neuropeptide binding; receptor binding

Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; synaptic transmission
 Sstr3 ELISA Kit
 Sstr3 Recombinant
 Sstr3 Antibody
 Smstr3 ELISA Kit
 Smstr3 Recombinant
 Smstr3 Antibody
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Somatostatin receptor type 4

 Somatostatin receptor type 4 ELISA Kit
 Somatostatin receptor type 4 Recombinant
 Somatostatin receptor type 4 Antibody
Also known as Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R).
SSTR4: Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative
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action of somatostatin in tumor cells. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: cytoplasm; integral to plasma membrane; neuron projection; plasma membrane

Molecular Function: neuropeptide binding; protein binding; somatostatin receptor activity

Biological Process: arachidonic acid metabolic process; cell migration; forebrain development; G-protein signaling, coupled to cyclic nucleotide second messenger; negative regulation of cAMP metabolic process; negative regulation of cell proliferation; positive regulation of MAPKKK cascade; synaptic transmission
 Sstr4 ELISA Kit
 Sstr4 Recombinant
 Sstr4 Antibody
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Somatostatin receptor type 5

 Somatostatin receptor type 5 ELISA Kit
 Somatostatin receptor type 5 Recombinant
 Somatostatin receptor type 5 Antibody
Also known as Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R).
Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization ().
 SSTR5 ELISA Kit
 SSTR5 Recombinant
 SSTR5 Antibody
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