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Son of sevenless

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Promotes the exchange of Ras-bound GDP by GTP (By similarity). May regulate signaling pathways downstream of receptor tyrosine kinase, egl-15 and let-23 .

Below are the list of possible Son of sevenless products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Son of sevenless homolog

 Son of sevenless homolog ELISA Kit
 Son of sevenless homolog Recombinant
 Son of sevenless homolog Antibody
Also known as Son of sevenless homolog (Guanine nucleotide exchange factor for RAS).
Promotes the exchange of Ras-bound GDP by GTP (). May regulate signaling pathways downstream of receptor tyrosine kinase, egl-15 and let-23 (PubMed:10880441). Required for larval and male spicule development, fluid homeostasis, vulva induction, spermatogenesis, and oogenesis by promoting meiosis prophase exit during oocyte maturation (PubMed:10880441, PubMed:17339331). Required for the delamination of G1 cell by promoting the loss of cell junctions and detachment from the excretory system during larval deve
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lopment (PubMed:25371363). Plays a role in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine (PubMed:15990870). Regulates synaptic levels of nAchR subunit lev-1 in the nerve cord (PubMed:15990870).
 sos-1 ELISA Kit
 sos-1 Recombinant
 sos-1 Antibody
 let-341 ELISA Kit
 let-341 Recombinant
 let-341 Antibody
 T28F12.3 ELISA Kit
 T28F12.3 Recombinant
 T28F12.3 Antibody
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Son of sevenless homolog 1

 Son of sevenless homolog 1 ELISA Kit
 Son of sevenless homolog 1 Recombinant
 Son of sevenless homolog 1 Antibody
Also known as Son of sevenless homolog 1 (SOS-1).
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for G
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DP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]
 SOS1 ELISA Kit
 SOS1 Recombinant
 SOS1 Antibody
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Son of sevenless homolog 2

 Son of sevenless homolog 2 ELISA Kit
 Son of sevenless homolog 2 Recombinant
 Son of sevenless homolog 2 Antibody
Also known as Son of sevenless homolog 2 (SOS-2).
SOS2: a guanine nucleotide exchange factor that activates Ras by catalyzing the exchange of bound GDP for GTP. Interacts with GRB2.

Protein type: Adaptor/scaffold; GEFs; GEFs, Ras; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q21

Cellular Component: cytosol

Molecular Function: guanyl-nucleoti
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de exchange factor activity; protein binding; Rho guanyl-nucleotide exchange factor activity

Biological Process: positive regulation of apoptosis; regulation of small GTPase mediated signal transduction

Disease: Noonan Syndrome 9
 SOS2 ELISA Kit
 SOS2 Recombinant
 SOS2 Antibody
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