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SPARC

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Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.

Below are the list of possible SPARC products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

SPARC

 SPARC ELISA Kit
 SPARC Recombinant
 SPARC Antibody
Also known as SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine).
SPARC: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that bind
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s 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity. Belongs to the SPARC family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: cell surface; cytoplasm; extracellular space; intracellular; nuclear matrix; nucleus; platelet alpha granule membrane; proteinaceous extracellular matrix; vesicle

Molecular Function: calcium ion binding; collagen binding; extracellular matrix binding; protein binding

Biological Process: lung development; negative regulation of angiogenesis; negative regulation of endothelial cell proliferation; regulation of cell morphogenesis; regulation of cell proliferation
 Sparc ELISA Kit
 Sparc Recombinant
 Sparc Antibody
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