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Sphingomyelin synthase-related protein

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sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphatidylethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway (By similarity).

Below are the list of possible Sphingomyelin synthase-related protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Sphingomyelin synthase-related protein 1

 Sphingomyelin synthase-related protein 1 ELISA Kit
 Sphingomyelin synthase-related protein 1 Recombinant
 Sphingomyelin synthase-related protein 1 Antibody
Also known as Sphingomyelin synthase-related protein 1 (SMSr) (Ceramide phosphoethanolamine synthase) (CPE synthase) (Sterile alpha motif domain-containing protein 8) (SAM domain-containing protein 8).
SAMD8: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase th
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at has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway. Belongs to the sphingomyelin synthase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: integral to endoplasmic reticulum membrane; integral to Golgi membrane; integral to plasma membrane

Molecular Function: ceramide cholinephosphotransferase activity; sphingomyelin synthase activity

Biological Process: ceramide biosynthetic process
 Samd8 ELISA Kit
 Samd8 Recombinant
 Samd8 Antibody
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