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Spindle and kinetochore-associated protein

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Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation .

Below are the list of possible Spindle and kinetochore-associated protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Spindle and kinetochore-associated protein 1

 Spindle and kinetochore-associated protein 1 ELISA Kit
 Spindle and kinetochore-associated protein 1 Recombinant
 Spindle and kinetochore-associated protein 1 Antibody
SKA1: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and d
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irectly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules. Belongs to the SKA1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: cytosol; outer kinetochore of condensed chromosome; spindle microtubule

Molecular Function: microtubule binding; protein binding

Biological Process: cell division; chromosome segregation; mitosis; regulation of microtubule polymerization or depolymerization; sister chromatid cohesion
 SKA1 ELISA Kit
 SKA1 Recombinant
 SKA1 Antibody
 C18orf24 ELISA Kit
 C18orf24 Recombinant
 C18orf24 Antibody
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Spindle and kinetochore-associated protein 1 homolog

 Spindle and kinetochore-associated protein 1 homolog ELISA Kit
 Spindle and kinetochore-associated protein 1 homolog Recombinant
 Spindle and kinetochore-associated protein 1 homolog Antibody
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Spindle and kinetochore-associated protein 2

 Spindle and kinetochore-associated protein 2 ELISA Kit
 Spindle and kinetochore-associated protein 2 Recombinant
 Spindle and kinetochore-associated protein 2 Antibody
Also known as Spindle and kinetochore-associated protein 2 (Protein FAM33A).
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres
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along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization. Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules.
 SKA2 ELISA Kit
 SKA2 Recombinant
 SKA2 Antibody
 FAM33A ELISA Kit
 FAM33A Recombinant
 FAM33A Antibody
 QtsA-12610 ELISA Kit
 QtsA-12610 Recombinant
 QtsA-12610 Antibody
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Spindle and kinetochore-associated protein 3

 Spindle and kinetochore-associated protein 3 ELISA Kit
 Spindle and kinetochore-associated protein 3 Recombinant
 Spindle and kinetochore-associated protein 3 Antibody
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coup
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led manner. In the complex, it mediates the microtubule-stimulated oligomerization. Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules.
 SKA3 ELISA Kit
 SKA3 Recombinant
 SKA3 Antibody
 RAMA1 ELISA Kit
 RAMA1 Recombinant
 RAMA1 Antibody
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