| Stabilin-2 ELISA Kit|
|Also known as Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis). |
STAB2: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipop
rotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 12q23.3
Cellular Component: cytoplasm; external side of plasma membrane; integral to plasma membrane; plasma membrane
Molecular Function: hyaluronic acid binding; low-density lipoprotein binding; low-density lipoprotein receptor activity; protein binding; scavenger receptor activity
Biological Process: defense response to bacterium; endocytosis; hyaluronan catabolic process; receptor-mediated endocytosis; regulation of blood coagulation; regulation of gene expression
| STAB2 ELISA Kit|
| FEEL2 ELISA Kit|
| FELL ELISA Kit|
| FEX2 ELISA Kit|