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Stabilin

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Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system (By similarity).

Below are the list of possible Stabilin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Stabilin-1

 Stabilin-1 ELISA Kit
 Stabilin-1 Recombinant
 Stabilin-1 Antibody
Also known as Stabilin-1 (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1) (FEEL-1).
STAB1: Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decreas
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e in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: cytoplasm; integral to plasma membrane

Molecular Function: low-density lipoprotein binding; low-density lipoprotein receptor activity; scavenger receptor activity

Biological Process: cell-cell signaling; defense response to bacterium; negative regulation of angiogenesis
 Stab1 ELISA Kit
 Stab1 Recombinant
 Stab1 Antibody
 Feel1 ELISA Kit
 Feel1 Recombinant
 Feel1 Antibody
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Stabilin-2

 Stabilin-2 ELISA Kit
 Stabilin-2 Recombinant
 Stabilin-2 Antibody
Also known as Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis).
STAB2: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipop
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rotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 12q23.3

Cellular Component: cytoplasm; external side of plasma membrane; integral to plasma membrane; plasma membrane

Molecular Function: hyaluronic acid binding; low-density lipoprotein binding; low-density lipoprotein receptor activity; protein binding; scavenger receptor activity

Biological Process: defense response to bacterium; endocytosis; hyaluronan catabolic process; receptor-mediated endocytosis; regulation of blood coagulation; regulation of gene expression
 STAB2 ELISA Kit
 STAB2 Recombinant
 STAB2 Antibody
 FEEL2 ELISA Kit
 FEEL2 Recombinant
 FEEL2 Antibody
 FELL ELISA Kit
 FELL Recombinant
 FELL Antibody
 FEX2 ELISA Kit
 FEX2 Recombinant
 FEX2 Antibody
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