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STAM-binding protein

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Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7 (By similarity). Involved in the ubiquitin-dependent sorting and trafficking of receptors from endosomes to lysosome. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization. Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways (By similarity).

Below are the list of possible STAM-binding protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

STAM-binding protein

 STAM-binding protein ELISA Kit
 STAM-binding protein Recombinant
 STAM-binding protein Antibody
Also known as STAM-binding protein (Associated molecule with the SH3 domain of STAM).
AMSH: an adaptor protein involved in cytokine signal transduction the JAK-STAT cascade. Binds to the SH3 domain of the signal-transducing adaptor molecule STAM (signal transducing adaptor molecule). May play a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression.

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rotein type: EC 3.1.2.15; EC 3.4.19.-; Protease; Ubiquitin-specific protease

Cellular Component: cleavage furrow; cytoplasm; nucleoplasm; plasma membrane

Molecular Function: protein domain specific binding; ubiquitin-specific protease activity

Biological Process: cytokinesis after mitosis; negative regulation of neuron apoptosis; negative regulation of phosphoinositide 3-kinase cascade; negative regulation of Ras protein signal transduction; protein deubiquitination
 Stambp ELISA Kit
 Stambp Recombinant
 Stambp Antibody
 Amsh ELISA Kit
 Amsh Recombinant
 Amsh Antibody
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STAM-binding protein-like

 STAM-binding protein-like ELISA Kit
 STAM-binding protein-like Recombinant
 STAM-binding protein-like Antibody
Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (). Functions at the endosome and is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes ().
 stambp ELISA Kit
 stambp Recombinant
 stambp Antibody
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STAM-binding protein-like A

 STAM-binding protein-like A ELISA Kit
 STAM-binding protein-like A Recombinant
 STAM-binding protein-like A Antibody
Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (). Functions at the endosome and is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes ().
 stambpa ELISA Kit
 stambpa Recombinant
 stambpa Antibody
 amsh ELISA Kit
 amsh Recombinant
 amsh Antibody
 stambp ELISA Kit
 stambp Recombinant
 stambp Antibody
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