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Stimulated by retinoic acid gene 6 protein

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May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity. Increases cellular retinol uptake from the retinol-RBP complex (By similarity).

Below are the list of possible Stimulated by retinoic acid gene 6 protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Stimulated by retinoic acid gene 6 protein

 Stimulated by retinoic acid gene 6 protein ELISA Kit
 Stimulated by retinoic acid gene 6 protein Recombinant
 Stimulated by retinoic acid gene 6 protein Antibody
Also known as Stimulated by retinoic acid gene 6 protein (Retinoic acid-responsive protein).
STRA6: May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high
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affinity. Increases cellular retinol uptake from the retinol-RBP complex. Defects in STRA6 are the cause of microphthalmia syndromic type 9 (MCOPS9); also called Matthew-Wood syndrome or Spear syndrome. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS9 is a rare clinical entity including as main characteristics anophthalmia or severe microphthalmia, and pulmonary hypoplasia or aplasia. Mutations in STRA6 may be a cause of isolated colobomatous microphthalmia, a disorder of the eye characterized by an abnormally small ocular globe. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: plasma membrane; protein complex

Molecular Function: protein binding

Biological Process: adrenal gland development; alveolus development; artery morphogenesis; blood vessel development; cognition; developmental growth; digestive tract morphogenesis; ear development; embryonic gut development; feeding behavior; female genitalia development; heart development; kidney development; learning; lung development; neuromuscular process; nose morphogenesis; positive regulation of behavior; positive regulation of JAK-STAT cascade; smooth muscle development; vocal learning
 Stra6 ELISA Kit
 Stra6 Recombinant
 Stra6 Antibody
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Stimulated by retinoic acid gene 6 protein homolog

 Stimulated by retinoic acid gene 6 protein homolog ELISA Kit
 Stimulated by retinoic acid gene 6 protein homolog Recombinant
 Stimulated by retinoic acid gene 6 protein homolog Antibody
May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity. Increases cellular retinol uptake from the retinol-RBP complex.
 STRA6 ELISA Kit
 STRA6 Recombinant
 STRA6 Antibody
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