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Stromelysin

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Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.

Below are the list of possible Stromelysin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Stromelysin-1

 Stromelysin-1 ELISA Kit
 Stromelysin-1 Recombinant
 Stromelysin-1 Antibody
Also known as Stromelysin-1 (SL-1) (EMS-2) (Matrix metalloproteinase-3) (MMP-3) (Transin-1).
MMP3: Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. Defects in MMP3 are the cause of susceptibility to coronary heart disease type 6 (CHDS6). A multifactorial disease characterized by an imbalanc
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e between myocardial functional requirements and the capacity of the coronary vessels to supply sufficient blood flow. Decreased capacity of the coronary vessels is often associated with thickening and loss of elasticity of the coronary arteries. A polymorphism in the MMP3 promoter region is associated with the risk of coronary heart disease and myocardial infarction, due to lower MMP3 proteolytic activity and higher extracellular matrix deposition in atherosclerotic lesions. Belongs to the peptidase M10A family.

Protein type: EC 3.4.24.17; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide

Cellular Component: cytosol; dendrite; extracellular space; mitochondrion; nucleus; protein complex

Molecular Function: endopeptidase activity; protein complex binding

Biological Process: negative regulation of protein kinase B signaling cascade; positive regulation of cell migration; positive regulation of protein oligomerization; protein catabolic process; proteolysis; regulation of cell migration
 Mmp3 ELISA Kit
 Mmp3 Recombinant
 Mmp3 Antibody
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Stromelysin-2

 Stromelysin-2 ELISA Kit
 Stromelysin-2 Recombinant
 Stromelysin-2 Antibody
Also known as Stromelysin-2 (SL-2) (Matrix metalloproteinase-10) (MMP-10) (Transformation-associated protein 34A) (Transin-2).
enzyme and a transformation-associated protein; activates procollagenase and degrades fibronectin and some gelatins [RGD, Feb 2006]
 Mmp10 ELISA Kit
 Mmp10 Recombinant
 Mmp10 Antibody
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Stromelysin-3

 Stromelysin-3 ELISA Kit
 Stromelysin-3 Recombinant
 Stromelysin-3 Antibody
Also known as Stromelysin-3 (SL-3) (ST3) (Matrix metalloproteinase-11) (MMP-11).
MMP11: May play an important role in the progression of epithelial malignancies. Belongs to the peptidase M10A family.

Protein type: EC 3.4.24.-; Extracellular matrix; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 22q11.23

Cellular Component: extracellular
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region; Golgi lumen; proteinaceous extracellular matrix

Molecular Function: serine-type endopeptidase activity

Biological Process: collagen catabolic process; extracellular matrix disassembly
 MMP11 ELISA Kit
 MMP11 Recombinant
 MMP11 Antibody
 STMY3 ELISA Kit
 STMY3 Recombinant
 STMY3 Antibody
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