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Suppressor of IKBKE

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Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).

Below are the list of possible Suppressor of IKBKE products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Suppressor of IKBKE 1

 Suppressor of IKBKE 1 ELISA Kit
 Suppressor of IKBKE 1 Recombinant
 Suppressor of IKBKE 1 Antibody
Also known as Suppressor of IKBKE 1 (Suppressor of IKK-epsilon).
SIKE: Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does
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not inhibit NF-kappa-B activation pathways. Belongs to the SIKE family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion
 Sike1 ELISA Kit
 Sike1 Recombinant
 Sike1 Antibody
 Sike ELISA Kit
 Sike Recombinant
 Sike Antibody
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