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T-cell acute lymphocytic leukemia protein 1 homolog ELISA Kit T-cell acute lymphocytic leukemia protein 1 homolog Recombinant T-cell acute lymphocytic leukemia protein 1 homolog Antibody | Also known as T-cell acute lymphocytic leukemia protein 1 homolog (TAL-1) (Stem cell protein). TAL1: a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.
Protein type: DNA-binding; Oncoprotein; Transcription factor
Cellular Component: histone >>> deacetylase complex; nuclear chromatin; nucleus; protein complex; transcription factor complex
Molecular Function: chromatin binding; DNA binding; enzyme binding; histone deacetylase binding; protein binding; protein heterodimerization activity; transcription factor activity
Biological Process: angiogenesis; astrocyte fate commitment; cell fate commitment; embryonic hemopoiesis; erythrocyte differentiation; erythrocyte maturation; generation of neurons; hemopoiesis; locomotory behavior; megakaryocyte differentiation; myeloid cell differentiation; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; platelet formation; positive regulation of cell division; positive regulation of chromatin assembly or disassembly; positive regulation of erythrocyte differentiation; positive regulation of mitotic cell cycle; positive regulation of protein complex assembly; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of cell proliferation; regulation of myeloid cell differentiation; regulation of transcription from RNA polymerase II promoter; spinal cord association neuron differentiation |
Tal1 ELISA Kit Tal1 Recombinant Tal1 Antibody | Scl ELISA Kit Scl Recombinant Scl Antibody |
Tal-1 ELISA Kit Tal-1 Recombinant Tal-1 Antibody |
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