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T-cell differentiation antigen

Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria. LPS binding leads to the activation of signaling cascades and down-stream MAP kinases. Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS.

Below are the list of possible T-cell differentiation antigen products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

T-cell differentiation antigen CD6

 T-cell differentiation antigen CD6 ELISA Kit
 T-cell differentiation antigen CD6 Recombinant
 T-cell differentiation antigen CD6 Antibody
Also known as T-cell differentiation antigen CD6 (CD antigen CD6).
CD6: a type I membrane protein involved in cell adhesion. Binds to CD166. Expressed on thymocytes, peripheral T cells, a subset of B cells, and a subset of neurons. Mediates the binding of developing thymocytes with thymic epithelial cells. CD6- T cells are less autoreactive than CD6+ T cells. Phosphorylated on tyrosines and ser
ines following T cell antigen receptor signaling. Five splice-variant isoforms have been described.

Protein type: Cell surface; Membrane protein, integral

Cellular Component: immunological synapse; intrinsic to plasma membrane; T cell receptor complex

Molecular Function: glycoprotein binding; lipopolysaccharide binding; protein binding; protein kinase binding

Biological Process: acute inflammatory response to antigenic stimulus; formation of immunological synapse; heterophilic cell adhesion; lipopolysaccharide-mediated signaling pathway; positive regulation of protein amino acid phosphorylation; positive regulation of T cell proliferation; response to lipopolysaccharide
 Cd6 ELISA Kit
 Cd6 Recombinant
 Cd6 Antibody
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