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T-lymphoma invasion and metastasis-inducing protein

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Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Required for normal cell adhesion and cell migration.

Below are the list of possible T-lymphoma invasion and metastasis-inducing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

T-lymphoma invasion and metastasis-inducing protein 1

 T-lymphoma invasion and metastasis-inducing protein 1 ELISA Kit
 T-lymphoma invasion and metastasis-inducing protein 1 Recombinant
 T-lymphoma invasion and metastasis-inducing protein 1 Antibody
Also known as T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1).
TIAM1: modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Regulates migration,
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cell-matrix and cell-cell adhesion by modulating the actin cytoskeleton through the GTPase, Rac1. Binding to Rac1 and the Arp2/3 complex may drive actin polymerization at specific sites, thus inducing dynamic morphological changes.

Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis; Oncoprotein

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: cytosol; extrinsic to internal side of plasma membrane; intercellular junction; plasma membrane

Molecular Function: guanyl-nucleotide exchange factor activity; kinase binding; protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity

Biological Process: cell migration; cell-matrix adhesion; ephrin receptor signaling pathway; positive regulation of apoptosis; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of protein binding; Rac protein signal transduction; regulation of small GTPase mediated signal transduction
 TIAM1 ELISA Kit
 TIAM1 Recombinant
 TIAM1 Antibody
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T-lymphoma invasion and metastasis-inducing protein 2

 T-lymphoma invasion and metastasis-inducing protein 2 ELISA Kit
 T-lymphoma invasion and metastasis-inducing protein 2 Recombinant
 T-lymphoma invasion and metastasis-inducing protein 2 Antibody
Also known as T-lymphoma invasion and metastasis-inducing protein 2 (TIAM-2) (SIF and TIAM1-like exchange factor).
This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, J
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ul 2008]
 TIAM2 ELISA Kit
 TIAM2 Recombinant
 TIAM2 Antibody
 KIAA2016 ELISA Kit
 KIAA2016 Recombinant
 KIAA2016 Antibody
 STEF ELISA Kit
 STEF Recombinant
 STEF Antibody
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