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Tau-tubulin kinase

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Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU (By similarity).

Below are the list of possible Tau-tubulin kinase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Tau-tubulin kinase 1

 Tau-tubulin kinase 1 ELISA Kit
 Tau-tubulin kinase 1 Recombinant
 Tau-tubulin kinase 1 Antibody
TTBK1: Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: CK1 group; EC 2.7.11.1; Kinase, protein; Protein kinase, CK1; Protein kinase, Ser/Thr (non-re
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ceptor); TTBK family

Cellular Component: cytoplasm; nucleus

Molecular Function: protein serine/threonine kinase activity

Biological Process: peptidyl-serine phosphorylation; regulation of cell shape
 Ttbk1 ELISA Kit
 Ttbk1 Recombinant
 Ttbk1 Antibody
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Tau-tubulin kinase 2

 Tau-tubulin kinase 2 ELISA Kit
 Tau-tubulin kinase 2 Recombinant
 Tau-tubulin kinase 2 Antibody
TTBK2: Serine/threonine kinase which is able to phosphorylate tau on serines. Defects in TTBK2 are the cause of spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebell
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um with variable involvement of the brainstem and spinal cord. SCA11 is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: CK1 group; EC 2.7.11.1; Kinase, protein; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor); TTBK family

Chromosomal Location of Human Ortholog: 15q15.2

Cellular Component: centriole; cytosol; extracellular space; nucleus

Molecular Function: protein binding; protein serine/threonine kinase activity

Biological Process: peptidyl-serine phosphorylation; regulation of cell shape; smoothened signaling pathway

Disease: Spinocerebellar Ataxia 11
 TTBK2 ELISA Kit
 TTBK2 Recombinant
 TTBK2 Antibody
 KIAA0847 ELISA Kit
 KIAA0847 Recombinant
 KIAA0847 Antibody
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